CD33 Mouse Monoclonal Antibody [Clone ID: HIM3-4]
CAT#: SM3084P
CD33 mouse monoclonal antibody, clone HIM3-4, Purified
Conjugation: Biotin
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SM3084P is a replacement of TA320261.
CNY 3,280.00
货期*
5周
规格
Specifications
Product Data | |
Clone Name | HIM3-4 |
Applications | FC |
Recommend Dilution | Flow Cytometry. |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | NFMY-9s human cell line |
Specificity | The antibody HIM3-4 reacts with CD33, a 67 kDa type I transmembrane glycoprotein (immunoglobulin superfamily) expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells and mast cells; it is absent on platelets, lymphocytes, erythrocytes and hematopoietic stem cells. |
Formulation | PBS, pH~7.4 State: Purified State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE) Preservative: 15 mM Sodium Azide |
Concentration | lot specific |
Purification | Affinity Chromatography on Protein A |
Conjugation | Unconjugated |
Storage Condition | Store undiluted at 2-8°C. DO NOT FREEZE! |
Gene Name | CD33 molecule |
Database Link | |
Background | CD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immunoreceptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies; these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia. |
Synonyms | Siglec-3, gp67 |
Reference Data |
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