EGR2 Mouse Monoclonal Antibody [Clone ID: OTI1B12]

Specifications

Product Data
Clone Name	OTI1B12
Applications	IF, IHC, WB
Recommend Dilution	WB: 1:500, IHC: 1:150, IF: 1:50-1:100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 156-476 of human EGR2(NP_000390) produced in E.coli.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	50.1 kDa
Gene Name	early growth response 2
Database Link	NP_000390 Entrez Gene 13654 MouseEntrez Gene 114090 RatEntrez Gene 1959 Human UniProt ID P11161
Background	The protein encoded by this gene is a transcription factor with three tandem C2H2-type zinc fingers. Defects in this gene are associated with Charcot-Marie-Tooth disease type 1D (CMT1D), Charcot-Marie-Tooth disease type 4E (CMT4E), and with Dejerine-Sottas syndrome (DSS). Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
Synonyms	AT591; CMT1D; CMT4E; KROX20
Reference Data
Protein Families	Druggable Genome, Transcription Factors

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