SOD2 Mouse Monoclonal Antibody [Clone ID: OTI1H6]

Specifications

Product Data
Clone Name	OTI1H6
Applications	WB
Recommend Dilution	WB 1:500~2000
Reactivity	Human, Dog
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human SOD2 (NP_000627) produced in HEK293T cell.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	22.2 kDa
Gene Name	superoxide dismutase 2
Database Link	NP_000627 Entrez Gene 476258 DogEntrez Gene 6648 Human UniProt ID P04179
Background	This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]
Synonyms	IPOB; MNSOD; MVCD6
Reference Data
Protein Families	Druggable Genome, Transcription Factors
Protein Pathways	Huntington's disease

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