Mycobacterium tuberculosis (all antigens) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA
Recommend Dilution	Suitable for immunohistochemistry and IFA.
Reactivity	Mycobacterium tuberculosis
Host	Rabbit
Clonality	Polyclonal
Immunogen	Purified PPD
Specificity	Minimum of 2 major M. tuberculosis bands by immunoelectrophoresis (gamma & beta). This antiserum has not been absorbed and may react with related species. Reactive with other Mycobacteria species including M. avium, M. phlei and M. parafortuitum. Antibody is non-reactive with E. coli K12, Salmonella typhimurium, Pseudomonas aeruginosa, Streptococcus (group B), Candida albicans and Neisseria meningitidis.
Formulation	PBS containing 10 mg/ml BSA as stabilizer and 0.002 % Thimerosal as preservative. Label: HRP State: Liquid purified Ig fraction. Label: Purified IgG fraction covalently coupled to a highly purified preparation of Horseradish Peroxidase (RZ>3). Care is taken to ensure adequate conjugation while preserving maximum enzyme activity. Free enzyme is removed Molar radio: HRP: IgG substitution is 2-3
Concentration	lot specific
Conjugation	HRP
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliqquots) at -20°C for longer. Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.
Background	Mycobacterium tuberculosis is the most common cause of tuberculosis. Primary infection begins with inhalation of 1 to 10 aerosolised bacilli. The pathogenicity of the organism is determined by its ability to escape host immune responses as well as eliciting delayed hypersensitivity. Alveolar macrophages engulf the invading cells but are unable to mount an effective defense. Several virulence factors are responsible for this apparent failure; most notably in the mycobacterial cell wall are the cord factor, lipoarabinomannan, and the 65 kd heat shock protein or HSP65.
Synonyms	M. tuberculosis, TB
Reference Data

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