Mycobacterium tuberculosis (all antigens) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC
Recommend Dilution	Immunofluorescence. Immunohistochemistry on Paraffin Sections.
Reactivity	Mycobacterium tuberculosis
Host	Rabbit
Clonality	Polyclonal
Immunogen	Purified PPD
Specificity	Specific for Mycobacterium tuberculosis (all antigens). Minimum of 2 major M. tuberculosis bands by Immunoelectrophoresis (gamma & beta). This antiserum has not been adsorbed and may react with related species. Reactive with other Mycobacteria including M. avium, M. phlei, M. parafortiutum. Non reactive with E. coli K12, Salmonella thyphimurium, Pseudomonas aeruginosa, Streptococcus B, Candida albicans, and Neisseria meningitidis.
Formulation	0.01M PBS, pH 7.2 with 0.09% Sodium Azide as preservative. No stabilizing proteins added. State: Purified State: Liquid purified Ig fraction (>95% pure)
Concentration	lot specific
Purification	Protein A Chromatography.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Background	Mycobacterium tuberculosis is the most common cause of tuberculosis. Primary infection begins with inhalation of 1 to 10 aerosolised bacilli. The pathogenicity of the organism is determined by its ability to escape host immune responses as well as eliciting delayed hypersensitivity. Alveolar macrophages engulf the invading cells but are unable to mount an effective defense. Several virulence factors are responsible for this apparent failure; most notably in the mycobacterial cell wall are the cord factor, lipoarabinomannan, and the 65 kd heat shock protein or HSP65.
Synonyms	M. tuberculosis, TB
Reference Data

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