Neisseria gonorrhoeae (all antigens) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA
Recommend Dilution	Suitable for use in immunocytochemistry and ELISA.
Reactivity	Neisseria gonorrhoeae
Host	Rabbit
Clonality	Polyclonal
Immunogen	Whole N. gonorrhoeae; ATCC 31426
Specificity	All antigens. This antiserum has not been absorbed and may react with related microorganisms.
Formulation	PBS containing 10 mg/ml BSA as stabilizer and 0.002 % Thimerosal as preservative. Label: HRP State: Liquid purified Ig fraction. Label: Highly purified preparation of horseradish peroxidase (RZ>3). Care is taken to ensure adequate conjugation while preserving maximum enzyme activity. Free enzyme is absent Molar radio: HRP:IgG substitution is 2-3.
Concentration	lot specific
Conjugation	HRP
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Background	Neisseria gonorrhoeae infections are acquired by sexual contact and usually affect the mucous membranes of the urethra in males and the endocervix and urethra in females, although the infection may disseminate to a variety of tissues. The pathogenic mechanism involves the attachment of the bacterium to nonciliated epithelial cells via pili (fimbriae) and the production of lipopolysaccharide endotoxin. Similarly, the lipopolysaccharide of Neisseria meningitidis is highly toxic, as it has an additional virulence factor in the form of its antiphagocytic capsule. Both pathogens produce IgA proteases which promote virulence. Many normal individuals may harbor Neisseria meningitidis in the upper respiratory tract, but Neisseria gonorrhoeae is never part of the normal flora and is only found after sexual contact with an infected person (or direct contact, in the case of infections in the newborn).
Reference Data

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