Neisseria gonorrhoeae (all antigens) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF
Recommend Dilution	Suitable for use in IFA. Also suitable for conjugation purposes.
Reactivity	Neisseria gonorrhoeae
Host	Rabbit
Clonality	Polyclonal
Immunogen	Whole N. gonorrhoeae; ATCC 31426
Specificity	All antigens. Antiserum is not absorbed and may react with related microorganisms.
Formulation	0.01 M PBS, pH 7.2, containing 0.09 % Sodium azide as preservative. State: Purified State: Liquid purified Ig fraction (>95% pure).
Concentration	lot specific
Purification	Protein A chromatography.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Background	Neisseria gonorrhoeae infections are acquired by sexual contact and usually affect the mucous membranes of the urethra in males and the endocervix and urethra in females, although the infection may disseminate to a variety of tissues. The pathogenic mechanism involves the attachment of the bacterium to nonciliated epithelial cells via pili (fimbriae) and the production of lipopolysaccharide endotoxin. Similarly, the lipopolysaccharide of Neisseria meningitidis is highly toxic, as it has an additional virulence factor in the form of its antiphagocytic capsule. Both pathogens produce IgA proteases which promote virulence. Many normal individuals may harbor Neisseria meningitidis in the upper respiratory tract, but Neisseria gonorrhoeae is never part of the normal flora and is only found after sexual contact with an infected person (or direct contact, in the case of infections in the newborn).
Reference Data

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