HLA Class II DR Mouse Monoclonal Antibody [Clone ID: L243]

Specifications

Product Data
Clone Name	L243
Applications	FC
Recommend Dilution	Flow cytometry analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
Reactivity	Canine, Human, Primate
Host	Mouse
Clonality	Monoclonal
Immunogen	Human B lymphocytes
Specificity	This antibody recognizes specifically HLA-DR molecules, both peptide-loaded and empty.
Formulation	Phosphate buffered saline (PBS) Label: APC State: Liquid Ig fraction Preservative: 15 mM sodium azide Label: Conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use.
Conjugation	APC
Storage Condition	Store undiluted at 2-8°C. DO NOT FREEZE! This products is photosensitive and should be protected from light.
Background	HLA-DR, a member of MHC class II glycoproteins, that bind intracellularly processed peptides and present them to the Th cells, is composed of 36 kDa alpha chain and 27 kDa beta chain, both anchored in the plasma membrane. Together with other MHC II molecules HLA-DR plays a central role in the immune system. It is expressed on antigen-presenting cells (dendritic cells, B lymphocytes, monocytes, macrophages).
Synonyms	HLA-DR, HLA class II histocompatibility antigen DR, MHC class II antigen DR
Reference Data

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