Piccolo (PCLO) Mouse Monoclonal Antibody [Clone ID: PCLO-01]
CAT#: AM26707RP-N
Piccolo (PCLO) mouse monoclonal antibody, clone PCLO-01, PE
Conjugation: Unconjugated
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CNY 4,340.00
货期*
5周
规格
Specifications
Product Data | |
Clone Name | PCLO-01 |
Applications | FC |
Recommend Dilution | Flow cytometry. |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Human recombinant PCLO protein |
Specificity | This antibody PCLO-01 recognizes PCLO (Piccolo), a more than 400 kDa multidomain protein expressed mainly in the presynaptic cytomatrix of the neurons. |
Formulation | Phosphate buffered saline (PBS) Label: PE State: Liquid Ig fraction Stabilizer: 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) Preservative: 15 mM sodium azide |
Concentration | lot specific |
Purification | Size-exclusion chromatography |
Conjugation | PE |
Storage Condition | Store undiluted at 2-8°C. DO NOT FREEZE! This products is photosensitive and should be protected from light. |
Gene Name | piccolo presynaptic cytomatrix protein |
Database Link | |
Background | PCLO (piccolo, also known as aczonin) is a large (more than 400 kDa) multidomain protein of the presynaptic cytomatrix in neurons, that is present in all vertebrate synapses, but is absent from invertebrates. It contains zinc finger and coiled-coil sequences, as well as N-terminal glutamine-rich sequence, and C-terminal PDZ domain followed by two C2 domains (C2A and C2B). In vitro binding and transfection experiments suggested that PCLO binds to multiple proteins including profilin and L-type calcium channels. It is involved in neurotransmitter release and insulin secretion. |
Synonyms | Protein piccolo, Aczonin, ACZ, KIAA0559 |
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