TAPA1 (CD81) Mouse Monoclonal Antibody [Clone ID: M38]
CAT#: AM26031RP-N
TAPA1 (CD81) mouse monoclonal antibody, clone M38, PE
Conjugation: Unconjugated APC FITC
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CNY 4,340.00
Cited in 4 publications. |
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Specifications
Product Data | |
Clone Name | M38 |
Applications | FC |
Recommend Dilution | Flow Cytometry analysis of Human blood cells using 20 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests. |
Reactivity | Feline, Human, Rabbit |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | MOLT-4 (human T-ALL cell line) |
Specificity | This antibody CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells. |
Formulation | Phosphate buffered saline (PBS) solution containing 15mM sodium azide Label: PE State: Liquid purified Ig fraction Label: Conjugated with R-Phycoerythrin under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. |
Conjugation | PE |
Storage Condition | Store undiluted at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. |
Gene Name | CD81 molecule |
Database Link | |
Background | CD81 (TAPA-1), a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T and other cells – e.g. in muscles CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus. |
Synonyms | S5.7; TAPA-1; TAPA1; Tetraspanin-28; Tspan-28; TSPAN28 |
Reference Data | |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transmembrane |
Protein Pathways | B cell receptor signaling pathway |
Citations (4)
The use of this Antibodies has been cited in the following citations: |
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Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes
,Escola JM, Kleijmeer MJ, Stoorvogel W, Griffith JM, Yoshie O, Geuze HJ,
J. Biol. Chem.
,PubMed ID 9685355
[CD81]
|
Molecular analyses of the association of CD4 with two members of the transmembrane 4 superfamily, CD81 and CD82
,Imai T, Kakizaki M, Nishimura M, Yoshie O,
J. Immunol.
,PubMed ID 7636191
[CD81]
|
C33 antigen and M38 antigen recognized by monoclonal antibodies inhibitory to syncytium formation by human T cell leukemia virus type 1 are both members of the transmembrane 4 superfamily and associate with each other and with CD4 or CD8 in T ce
,Imai T, Yoshie O,
J. Immunol.
,PubMed ID 8245480
[CD81]
|
Identification of membrane antigen C33 recognized by monoclonal antibodies inhibitory to human T-cell leukemia virus type 1 (HTLV-1)-induced syncytium formation: altered glycosylation of C33 antigen in HTLV-1-positive T cells
,Fukudome K, Furuse M, Imai T, Nishimura M, Takagi S, Hinuma Y, Yoshie O,
J. Virol.
,PubMed ID 1738199
[CD81]
|
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