CD161 (KLRB1) Mouse Monoclonal Antibody [Clone ID: HP-3G10]

Specifications

Product Data
Clone Name	HP-3G10
Applications	FC
Recommend Dilution	Flow cytometry analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
Reactivity	Human, Primate
Host	Mouse
Clonality	Monoclonal
Immunogen	Human NK cells
Specificity	This antibody recognizes CD161, a type II transmembrane C-type lectin receptor, expressed on the plasma membrane of NK cells, dendritic cells, activated monocytes and a subset of T cells as a disulphide-linked homodimer.
Formulation	Phosphate buffered saline (PBS) Label: PE State: Liquid purified Ig fraction Stabilizer: 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) Preservative: 15 mM sodium azide Label: Conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
Conjugation	PE
Storage Condition	Store the antibody at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Gene Name	killer cell lectin like receptor B1
Database Link	Entrez Gene 3820 Human UniProt ID Q12918
Background	CD161, also known as Nkrp1 (natural killer receptor protein 1) or Klrb1 (killer cell lectin-like receptor subfamily b member 1), is a disulphide-linked homodimeric receptor, which is involved in regulation of NK cell and NKT cell function. It is expressed on a majority of NK cells, NKT cells, and e.g. Th17 cells and CD3+ thymocytes. Although rat CD161 has three isoforms (a, b, c), the human CD161 is expressed as one isoform.
Synonyms	HNKR-P1a, CLEC5B, NKRP1A
Reference Data

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