CD161 (KLRB1) Mouse Monoclonal Antibody [Clone ID: HP-3G10]

Specifications

Product Data
Clone Name	HP-3G10
Applications	FC, WB
Recommend Dilution	Flow cytometry. Western blot.
Reactivity	Human, Primate
Host	Mouse
Clonality	Monoclonal
Immunogen	Human NK cells
Specificity	This antibody recognizes CD161, a type II transmembrane C-type lectin receptor, expressed on the plasma membrane of NK cells, dendritic cells, activated monocytes and a subset of T cells as a disulphide-linked homodimer.
Formulation	Phosphate buffered saline (PBS) State: Purified State: Liquid Ig fraction Preservative: 15 mM sodium azide, approx. pH 7.4
Concentration	lot specific
Purification	Protein-A affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C. DO NOT FREEZE!
Gene Name	killer cell lectin like receptor B1
Database Link	Entrez Gene 3820 Human UniProt ID Q12918
Background	CD161, also known as Nkrp1 (natural killer receptor protein 1) or Klrb1 (killer cell lectin-like receptor subfamily b member 1), is a disulphide-linked homodimeric receptor, which is involved in regulation of NK cell and NKT cell function. It is expressed on a majority of NK cells, NKT cells, and e.g. Th17 cells and CD3+ thymocytes. Although rat CD161 has three isoforms (a, b, c), the human CD161 is expressed as one isoform.
Synonyms	HNKR-P1a, CLEC5B, NKRP1A
Reference Data

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