CD8 Mouse Monoclonal Antibody [Clone ID: EP72]
CAT#: AM08138PU-N
CD8 mouse monoclonal antibody, clone EP72, Purified
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CNY 4,862.00
货期*
4周
规格
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Specifications
Product Data | |
Clone Name | EP72 |
Applications | FC, IHC, IP |
Recommend Dilution | Flow Cytometry. (Ref.1-3) Immunoprecipitation. (Ref.1-3) Immunohistochemistry (Acetone-Fixed, Frozen Tissue Sections). Cell Sorting: Purification of CD8+ T cells. (Ref.1) |
Reactivity | Chicken |
Host | Mouse |
Clonality | Monoclonal |
Specificity | This antibody recognizes alpha chain (34-kDa) of Chicken CD8. |
Formulation | 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added. State: Purified State: Liquid purified Ig fraction. |
Concentration | lot specific |
Conjugation | Unconjugated |
Storage Condition | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Database Link | |
Background | The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. CD8 is expressed on most thymocytes and approximately 1/3 of peripheral blood T cells in humans. CD8 alpha/beta heterodimers are expressed only on TCR alpha/beta T cells, whereas CD8 alpha homodimers can be expressed on alpha/beta and gamma/delta T cells and some NK cells in humans. The pattern of expression in other species has not been well documented. |
Synonyms | CD8 alpha chain, CD8A, MAL |
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