CD8 Mouse Monoclonal Antibody [Clone ID: EP72]
CAT#: AM08138BT-N
CD8 mouse monoclonal antibody, clone EP72, Biotin
Conjugation: Unconjugated FITC PE
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CNY 5,841.00
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Specifications
Product Data | |
Clone Name | EP72 |
Applications | FC |
Recommend Dilution | Flow Cytometry: < / = 1 µg/10e6 cells. (Ref.1-3) |
Reactivity | Chicken |
Host | Mouse |
Clonality | Monoclonal |
Specificity | This antibody recognizes alpha chain (34-kDa) of Chicken CD8. |
Formulation | PBS containing 0.09% Sodium Azide as preservative. Label: Biotin State: Liquid purified Ig fraction. |
Concentration | lot specific |
Conjugation | Biotin |
Storage Condition | Store the antibody undiluted at 2-8°C for one month or in (aliquots) at -20°C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing. |
Database Link | |
Background | The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. CD8 is expressed on most thymocytes and approximately 1/3 of peripheral blood T cells in humans. CD8 alpha/beta heterodimers are expressed only on TCR alpha/beta T cells, whereas CD8 alpha homodimers can be expressed on alpha/beta and gamma/delta T cells and some NK cells in humans. The pattern of expression in other species has not been well documented. |
Synonyms | CD8 alpha chain, CD8A, MAL |
Reference Data |
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