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PD-L1
PD-L1 and PD-L2 ligands function as key check-point regulators of the immune system. Immunotherapy with PD-1 and PD-L1 blocking monoclonal antibodies have improved the anti-tumor activities of patients’ T-cells.
PD-L1 UltraMab™ Antibody
| SKU# | TA591004 |
|---|---|
| Clone Name | OR-5E3 |
| Target | Homo sapiens CD274 molecule (CD274), transcript variant 1 |
| Host | Rabbit |
| Reactivity | Human |
| Tested Application | IHC, ELISA |
| Dilution | IHC: 1:50-1:200 |
IHC staining of FFPE mouse spleen tissue with OR-5E3 shows positive staining of APC immune cells.
IHC staining of FFPE human Bladder cancer and Melanoma tissue with OR-5E3 and SP142 clone. OR-5E3 gives similar or stronger staining when compared to the FDA approved SP142 clone.
Antibodies against commonly studied proteins in cancer immunotherapy
| Protein Name | Antibody Description | SKU |
|---|---|---|
| ARG1 | ARG1 mouse monoclonal antibody, clone OTI4E6 | TA502413 |
| B7-1/CD80 | CD80 mouse monoclonal antibody, clone UMAB65 | UM500055 |
| B7-H3/CD276 | Rabbit Polyclonal CD276 Antibody | TA355034 |
| B7-H4/VTCN1 | Anti-VTCN1 mouse monoclonal antibody | TA318347 |
| CD160 | Rabbit Polyclonal Anti-CD160 Antibody | TA349762 |
| CD19 | CD19 mouse monoclonal antibody, clone UMAB103 | UM500071 |
| CD244 | Rabbit Polyclonal Anti-CD244 Antibody | TA349773 |
| IDO1 | IDO1 mouse monoclonal antibody, clone UMAB126 | UM500091 |
| IL-10RA | IL10RA mouse monoclonal antibody, clone OTI1D10 | TA506929 |
| IL-13 | IL13 mouse monoclonal antibody, clone OTI6D3 | TA804004 |
| IL-4 | Rabbit polyclonal IL4 Antibody (C-term) | TA324803 |
| LAG3 | LAG3 mouse monoclonal antibody, clone OTI8F6 | TA807082 |
| MICA | Rabbit Polyclonal MICA Antibody | TA306443 |
| MICB | anti MIC-B monoclonal antibody, cloneB-D55 | AM31286AF-N |
| N-Cadherin | NCAM1/CD56 mouse monoclonal antibody, clone UMAB194 | UM800086 |
| Notch1 | Anti-Notch1 mouse monoclonal antibody, clone OTI3E12 | TA500078 |
| PD-L1 | PD-L1/CD274 mouse monoclonal antibody, clone OTI13G7 | TA809809 |
| PD-L2 | PDL2/PDCD1LG2 mouse monoclonal antibody, clone OTI5A7 | TA808997 |
| SOX2 | Rabbit Polyclonal Antibody against SOX2 - Embryonic Stem Cell Marker | TA301462 |
| TIM3 | HAVCR2 mouse monoclonal antibody, clone OTI2E2 | TA807034 |
| Beta Tubulin | Rabbit polyclonal anti-TUBB(beta Tubulin) antibody, Loading control | TA301569 |
| Vimentin | Vimentin (VIM) mouse monoclonal antibody, clone UMAB160 | UM800055 |
