ATG7 Human siRNA Oligo Duplex (Locus ID 10533)
CAT#: SR323157
ATG7 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each
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SR323157 is the updated version of SR307159.
CNY 4,090.00
货期*
4周
规格
Cited in 2 publications. |
Product images
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经常一起买 (3)
Specifications
Product Data | |
Purity | HPLC purified |
Quality Control | Tested by ESI-MS |
Sequences | Available with shipment |
Stability | One year from date of shipment when stored at -20°C. |
# of transfections | Approximately 330 transfections/2nmol in 24-well plate under optimized conditions (final conc. 10 nM). |
Note | Single siRNA duplex (10nmol) can be ordered. |
Reference Data | |
RefSeq | NM_001136031, NM_001144912, NM_006395, NM_001349232, NM_001349233, NM_001349234, NM_001349235, NM_001349236, NM_001349237, NM_001349238 |
Synonyms | APG7-LIKE; APG7L; GSA7 |
Components | ATG7 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 10533)Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmolIncluded - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml |
Summary | This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] |
Performance Guranteed | OriGene guarantees that at least two of the three Dicer-Substrate duplexes in the kit will provide at least 70% or more knockdown of the target mRNA when used at 10 nM concentration by quantitative RT-PCR when the TYE-563 fluorescent transfection control duplex (cat# SR30002) indicates that >90% of the cells have been transfected and the HPRT positive control (cat# SR30003) provides 90% knockdown efficiency. For non-conforming siRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the siRNA kit. To arrange for a free replacement with newly designed duplexes, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled siRNA control (quantitative RT-PCR data required). |
Citations (2)
The use of this RNAi has been cited in the following citations: |
---|
Macroautophagy Regulates Nuclear NOTCH1 Activity Through Multiple p62 Binding Sites
,Zhang, T;Guo, L;Wang, Y;Yang, Y;,
IUBMB Life
,PubMed ID 30207627
[ATG7]
|
The Vici syndrome protein EPG5 regulates intracellular nucleic acid trafficking linking autophagy to innate and adaptive immunity
,null,
Autophagy
,PubMed ID 29130391
[ATG7]
|
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