TCF21 Human siRNA Oligo Duplex (Locus ID 6943)
CAT#: SR321985
TCF21 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each
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SR321985 is the updated version of SR304753.
CNY 4,090.00
货期*
4周
规格
Cited in 6 publications. |
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经常一起买 (3)
Specifications
Product Data | |
Purity | HPLC purified |
Quality Control | Tested by ESI-MS |
Sequences | Available with shipment |
Stability | One year from date of shipment when stored at -20°C. |
# of transfections | Approximately 330 transfections/2nmol in 24-well plate under optimized conditions (final conc. 10 nM). |
Note | Single siRNA duplex (10nmol) can be ordered. |
Reference Data | |
RefSeq | NM_003206, NM_198392 |
Synonyms | bHLHa23; POD1 |
Components | TCF21 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 6943)Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmolIncluded - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml |
Summary | TCF21 encodes a transcription factor of the basic helix-loop-helix family. The TCF21 product is mesoderm specific, and expressed in embryonic epicardium, mesenchyme-derived tissues of lung, gut, gonad, and both mesenchymal and glomerular epithelial cells in the kidney. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
Performance Guranteed | OriGene guarantees that at least two of the three Dicer-Substrate duplexes in the kit will provide at least 70% or more knockdown of the target mRNA when used at 10 nM concentration by quantitative RT-PCR when the TYE-563 fluorescent transfection control duplex (cat# SR30002) indicates that >90% of the cells have been transfected and the HPRT positive control (cat# SR30003) provides 90% knockdown efficiency. For non-conforming siRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the siRNA kit. To arrange for a free replacement with newly designed duplexes, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled siRNA control (quantitative RT-PCR data required). |
Citations (6)
The use of this RNAi has been cited in the following citations: |
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The environment-sensing aryl-hydrocarbon receptor inhibits the chondrogenic fate of modulated smooth muscle cells in atherosclerotic lesions
,Kim, JB;Zhao,Q;Nguyen, T;Pjanic, M;Cheng, P;Wirka, R;Nagao, M;Kundu, R;Kim, JB;Falk, C;Quertermous, T;,
biorxiv.org
[TCF21]
|
The environment-sensing aryl-hydrocarbon receptor inhibits the chondrogenic fate of modulated smooth muscle cells in atherosclerotic lesions
,Kim, JB;Zhao, Q;Nguyen, T;Pjanic, M;Cheng, P;Wirka, R;,
bioRxiv
[TCF21]
|
TCF21 and AP-1 interact through epigenetic modifications to regulate coronary artery disease gene expression
,Zhao, Q;Wirka, R;Nguyen, T;Nagao, M;Cheng, P;Miller, CL;Kim, JB;Pjanic, M;Quertermous, T;,
Genome Med
,PubMed ID 31014396
[TCF21]
|
TCF21 and the environmental sensor aryl-hydrocarbon receptor cooperate to activate a pro-inflammatory gene expression program in coronary artery smooth muscle cells
,null,
PLoS Genetics
,PubMed ID 28481916
[TCF21]
|
Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells That Contribute to the Fibrous CapCharacterization of TCF21 downstream target regions identifies a transcriptional network linking multiple independent coronary artery disease loci
,null,
PLoS Genetics
,PubMed ID 26020946
[TCF21]
|
Coronary artery disease associated transcription factor TCF21 regulates smooth muscle precursor cells that contribute to the fibrous cap
,null,
Genomics Data
,PubMed ID 26090325
[TCF21]
|
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