STK33 Human siRNA Oligo Duplex (Locus ID 65975)
CAT#: SR312240
STK33 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each
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CNY 4,090.00
货期*
4周
规格
Cited in 1 publication. |
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经常一起买 (3)
Specifications
Product Data | |
Purity | HPLC purified |
Quality Control | Tested by ESI-MS |
Sequences | Available with shipment |
Stability | One year from date of shipment when stored at -20°C. |
# of transfections | Approximately 330 transfections/2nmol in 24-well plate under optimized conditions (final conc. 10 nM). |
Note | Single siRNA duplex (10nmol) can be ordered. |
Reference Data | |
RefSeq | NM_001289058, NM_001289059, NM_001289061, NM_030906, NM_001352387, NM_001352388, NM_001352389, NM_001352390, NM_001352391, NM_001352392, NM_001352393, NM_001352394, NM_001352395, NM_001352396, NM_001352397, NM_001352398, NM_001352399 |
Components | STK33 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 65975)Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmolIncluded - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml |
Summary | Serine/threonine protein kinase which phosphorylates VIME. May play a specific role in the dynamic behavior of the intermediate filament cytoskeleton by phosphorylation of VIME (By similarity). Not essential for the survival of KRAS-dependent AML cell lines.[UniProtKB/Swiss-Prot Function] |
Performance Guranteed | OriGene guarantees that at least two of the three Dicer-Substrate duplexes in the kit will provide at least 70% or more knockdown of the target mRNA when used at 10 nM concentration by quantitative RT-PCR when the TYE-563 fluorescent transfection control duplex (cat# SR30002) indicates that >90% of the cells have been transfected and the HPRT positive control (cat# SR30003) provides 90% knockdown efficiency. For non-conforming siRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the siRNA kit. To arrange for a free replacement with newly designed duplexes, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled siRNA control (quantitative RT-PCR data required). |
Citations (1)
The use of this RNAi has been cited in the following citations: |
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STK33 promotes growth and progression of pancreatic cancer as a critical downstream mediator of HIF-1α
,Kong, F;Kong, X;Du, Y;Chen, Y;Deng, X;Zhu, J;Du, J;Li, L;Jia, Z;Xie, D;Li, Z;Xie, K;,
Cancer Res.
,PubMed ID 29038348
[STK33]
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