ANKS1B Human siRNA Oligo Duplex (Locus ID 56899)

Specifications

Product Data
Purity	HPLC purified
Quality Control	Tested by ESI-MS
Sequences	Available with shipment
Stability	One year from date of shipment when stored at -20°C.
# of transfections	Approximately 330 transfections/2nmol in 24-well plate under optimized conditions (final conc. 10 nM).
Note	Single siRNA duplex (10nmol) can be ordered.
Reference Data
RefSeq	NM_001204065, NM_001204066, NM_001204067, NM_001204068, NM_001204069, NM_001204070, NM_001204079, NM_001204080, NM_001204081, NM_020140, NM_152788, NM_181670, NM_001352185, NM_001352186, NM_001352187, NM_001352188, NM_001352189, NM_001352190, NM_001352191, NM_001352192, NM_001352193, NM_001352194, NM_001352195, NM_001352196, NM_001352197, NM_001352198, NM_001352199, NM_001352200, NM_001352201, NM_001352202, NM_001352203, NM_001352204, NM_001352205, NM_001352206, NM_001352207, NM_001352208, NM_001352209, NM_001352210, NM_001352211, NM_001352212, NM_001352213, NM_001352214, NM_001352216, NM_001352217, NM_001352218, NM_001352219, NM_001352220, NM_001352221, NM_001352222, NM_001352223, NM_001352224, NM_001352225
Synonyms	AIDA; AIDA-1; ANKS2; cajalin-2; EB-1; EB1
Components	ANKS1B (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 56899) Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml
Summary	This gene encodes a multi-domain protein that is predominantly expressed in brain and testis. This protein interacts with amyloid beta protein precursor (AbetaPP) and may have a role in normal brain development, and in the pathogenesis of Alzheimer's disease. Expression of this gene has been shown to be elevated in patients with pre-B cell acute lymphocytic leukemia associated with t(1;19) translocation. Alternatively spliced transcript variants encoding different isoforms (some with different subcellular localization, PMID:15004329) have been described for this gene. [provided by RefSeq, Aug 2011]
Performance Guranteed	OriGene guarantees that at least two of the three Dicer-Substrate duplexes in the kit will provide at least 70% or more knockdown of the target mRNA when used at 10 nM concentration by quantitative RT-PCR when the TYE-563 fluorescent transfection control duplex (cat# SR30002) indicates that >90% of the cells have been transfected and the HPRT positive control (cat# SR30003) provides 90% knockdown efficiency. For non-conforming siRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the siRNA kit. To arrange for a free replacement with newly designed duplexes, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled siRNA control (quantitative RT-PCR data required).

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.