PXK Human siRNA Oligo Duplex (Locus ID 54899)

Specifications

Product Data
Purity	HPLC purified
Quality Control	Tested by ESI-MS
Sequences	Available with shipment
Stability	One year from date of shipment when stored at -20°C.
# of transfections	Approximately 330 transfections/2nmol in 24-well plate under optimized conditions (final conc. 10 nM).
Note	Single siRNA duplex (10nmol) can be ordered.
Reference Data
RefSeq	NM_001289095, NM_001289096, NM_001289098, NM_001289099, NM_001289100, NM_001289101, NM_017771, NM_001349488, NM_001349489, NM_001349490, NM_001349491, NM_001349492, NM_001349493, NM_001349494, NM_001349495, NM_001349496, NM_001349497, NM_001349498, NM_001349499, NM_001349500, NM_001349501, NM_001349502, NM_001349503, NM_001349504, NM_001349506, NM_001349507, NM_001349508, NM_001349509, NM_001349510, NM_001349511, NM_001349512, NM_001349513, NM_001349514, NM_001349515, NM_001349516, NM_001349517, NM_001349518, NM_001349519, NM_001349520, NM_001349521, NM_001349522, NM_001349524, NM_001349525, NM_001349526, NM_001349527, NM_001349528, NM_001349529, NM_001349530, NM_001349531, NM_001349532, NM_001349533, NM_001349534, NM_001349535, NM_001349536, NM_001349537, NM_001349538, NM_001349539, NM_001349540, NR_146193, NR_146194
Synonyms	MONAKA; SLOB
Components	PXK (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 54899) Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml
Summary	This gene encodes a phox (PX) domain-containing protein which may be involved in synaptic transmission and the ligand-induced internalization and degradation of epidermal growth factors. Variations in this gene may be associated with susceptibility to systemic lupus erythematosus (SLE). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Performance Guranteed	OriGene guarantees that at least two of the three Dicer-Substrate duplexes in the kit will provide at least 70% or more knockdown of the target mRNA when used at 10 nM concentration by quantitative RT-PCR when the TYE-563 fluorescent transfection control duplex (cat# SR30002) indicates that >90% of the cells have been transfected and the HPRT positive control (cat# SR30003) provides 90% knockdown efficiency. For non-conforming siRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the siRNA kit. To arrange for a free replacement with newly designed duplexes, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled siRNA control (quantitative RT-PCR data required).

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.