Aprataxin (APTX) Human siRNA Oligo Duplex (Locus ID 54840)

Specifications

Product Data
Purity	HPLC purified
Quality Control	Tested by ESI-MS
Sequences	Available with shipment
Stability	One year from date of shipment when stored at -20°C.
# of transfections	Approximately 330 transfections/2nmol in 24-well plate under optimized conditions (final conc. 10 nM).
Note	Single siRNA duplex (10nmol) can be ordered.
Reference Data
RefSeq	NM_001195248, NM_001195249, NM_001195250, NM_001195251, NM_001195252, NM_001195254, NM_017692, NM_175069, NM_175071, NM_175072, NM_175073, NR_036576, NR_036577, NR_036578, NR_036579, NM_001368995, NM_001368997, NM_001369000, NM_001369002, NM_001369004, NM_001369005, NM_001370670, NR_160920, NR_160922, NR_160923, NR_160930, NM_001368996, NM_001368998, NM_001368999, NM_001369001, NM_001369003, NM_001369006, NM_001370669, NM_001370673, NR_160921, NR_160924, NR_160925, NR_160926, NR_160927, NR_160928, NR_160929, NR_160931
Synonyms	AOA; AOA1; AXA1; EAOH; EOAHA; FHA-HIT
Components	APTX (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 54840) Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml
Summary	This gene encodes a member of the histidine triad (HIT) superfamily. The encoded protein may play a role in single-stranded DNA repair through its nucleotide-binding activity and its diadenosine polyphosphate hydrolase activity. Mutations in this gene have been associated with ataxia-ocular apraxia. Alternatively spliced transcript variants have been identified for this gene.[provided by RefSeq, Aug 2010]
Performance Guranteed	OriGene guarantees that at least two of the three Dicer-Substrate duplexes in the kit will provide at least 70% or more knockdown of the target mRNA when used at 10 nM concentration by quantitative RT-PCR when the TYE-563 fluorescent transfection control duplex (cat# SR30002) indicates that >90% of the cells have been transfected and the HPRT positive control (cat# SR30003) provides 90% knockdown efficiency. For non-conforming siRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the siRNA kit. To arrange for a free replacement with newly designed duplexes, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled siRNA control (quantitative RT-PCR data required).

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.