siRNA Related Product

CAT＃: SR30004

Trilencer-27 Universal scrambled negative control siRNA duplex - 2 nmol

Datasheet
SDS

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CNY 1,050.00

货期*
4周
规格
    • 2 nmol
Cited in 300 publications.

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Trilencer-27 Fluorescent-labeled transfection control siRNA duplex - 1 nmol
    • 1 nmol

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Specifications

Product Data
Quality Control This duplex was sequence verified and functionally validated.
Stability The control is stable for one year from date of shipping when stored at -20oC.
Note Single siRNA duplex (10nmol) can be ordered.
Reference Data
Components 1 vial of universal scrambled negative control siRNA duplex (2 nmol)
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (300)

The use of this RNAi has been cited in the following citations:
The E3 Ubiquitin Ligase TRIM21 Regulates Basal Levels of PDGFRβ. ,null, International journal of molecular sciences ,PubMed ID 37175489
Occludin Regulates HIV-1 Infection by Modulation of the Interferon Stimulated OAS Gene Family ,null, Molecular Neurobiology ,PubMed ID 37209263
PARP1 allows proper telomere replication through TRF1 poly (ADP-ribosyl)ation and helicase recruitment ,null, Communications Biology ,PubMed ID 36864251
Fibroblast growth factor 18 alleviates stress-induced pathological cardiac hypertrophy in male mice ,null, Nature Communications ,PubMed ID 36871047
Cytosolic aldose metabolism contributes to progression from cirrhosis to hepatocarcinogenesis. ,null, Nature metabolism ,PubMed ID 36658399
Overexpression of the pro‐protein convertase furin predicts prognosis and promotes papillary thyroid carcinoma progression and metastasis through RAF / MEK signaling ,null, Molecular Oncology ,PubMed ID 36799665
Formation of the glomerular microvasculature is regulated by VEGFR-3. ,null, American journal of physiology. Renal physiology ,PubMed ID 36395385
Spinal dopaminergic D 1 and D 5 receptors contribute to reserpine-induced fibromyalgia-like pain in rats. ,null, Brain research ,PubMed ID 36402178
FOXA1 is a transcriptional activator of Odf2/Cenexin and regulates primary ciliation ,null, Scientific Reports ,PubMed ID 36509813
Distinct roles of the Chlamydia trachomatis effectors TarP and TmeA in the regulation of formin and Arp2/3 during entry. ,null, Journal of cell science ,PubMed ID 36093837
Nanoliposome C6-Ceramide in combination with anti-CTLA4 antibody improves anti-tumor immunity in hepatocellular cancer ,null, FASEB journal : official publication of the Federation of American Societies for Experimental Biology ,PubMed ID 35294071
Mitochondrial reactive oxygen is critical for IL-12/IL-18-induced IFN-γ production by CD4+ T cells and is regulated by Fas/FasL signaling ,null, Cell Death & Disease ,PubMed ID 35668079
The lncRNA Punisher Regulates Apoptosis and Mitochondrial Homeostasis of Vascular Smooth Muscle Cells via Targeting miR-664a-5p and OPA1 ,null, Oxidative Medicine and Cellular Longevity ,PubMed ID 35663194
Maternal Exercise-Induced SOD3 Reverses the Deleterious Effects of Maternal High-Fat Diet on Offspring Metabolism Through Stabilization of H3K4me3 and Protection Against WDR82 Carbonylation. ,null, Diabetes ,PubMed ID 35290440
TET2-mediated epigenetic reprogramming of breast cancer cells impairs lysosome biogenesis ,null, Life Science Alliance ,PubMed ID 35351824
Dietary salt initiates redox signaling between endothelium and vascular smooth muscle through NADPH oxidase 4 ,null, Redox Biology ,PubMed ID 35378363
RelA Is an Essential Target for Enhancing Cellular Responses to the DNA Repair/Ref-1 Redox Signaling Protein and Restoring Perturbated Cellular Redox Homeostasis in Mouse PDAC Cells ,null, Frontiers in Oncology ,PubMed ID 35402225
ROS-induced PADI2 downregulation accelerates cellular senescence via the stimulation of SASP production and NFκB activation ,null, Cellular and Molecular Life Sciences ,PubMed ID 35218410
5-Lipoxygenase Inhibition Protects Retinal Pigment Epithelium from Sodium Iodate-Induced Ferroptosis and Prevents Retinal Degeneration ,null, Oxidative Medicine and Cellular Longevity ,PubMed ID 35251467
Autophagy mediates the clearance of oligodendroglial SNCA/alpha-synuclein and TPPP/p25A in multiple system atrophy models ,null, Autophagy ,PubMed ID 35000546
Interleukin 21 Receptor Affects Adipogenesis of Human Adipose-Derived Stem/Stromal Cells ,null, Stem Cells International ,PubMed ID 35047041
Platelet PD-L1 reflects collective intratumoral PD-L1 expression and predicts immunotherapy response in non-small cell lung cancer ,null, Nature Communications ,PubMed ID 34853305
Loss of peptidase D binding restores the tumor suppressor functions of oncogenic p53 mutants ,null, Communications Biology ,PubMed ID 34880421
Exendin-4 Preserves Blood-Brain Barrier Integrity via Glucagon-Like Peptide 1 Receptor/Activated Protein Kinase-Dependent Nuclear Factor-Kappa B/Matrix Metalloproteinase-9 Inhibition After Subarachnoid Hemorrhage in Rat ,null, Frontiers in Molecular Neuroscience ,PubMed ID 35002615
Keratin 19 interacts with GSK3β to regulate its nuclear accumulation and degradation of cyclin D3 ,null, Molecular Biology of the Cell ,PubMed ID 34406791
Loss of ZNF677 expression is a predictive biomarker for lymph node metastasis in Middle Eastern Colorectal Cancer ,null, Scientific Reports ,PubMed ID 34785764
SPARC Aggravates Blood-Brain Barrier Disruption via Integrin αVβ3/MAPKs/MMP-9 Signaling Pathway after Subarachnoid Hemorrhage ,null, Oxidative Medicine and Cellular Longevity ,PubMed ID 34804372
Low-flow intussusception and metastable VEGFR2 signaling launch angiogenesis in ischemic muscle ,null, Science Advances ,PubMed ID 34826235
Characterization and prognostic value of LXR splice variants in triple-negative breast cancer ,null, iScience ,PubMed ID 34755086
IL-27 Derived From Macrophages Facilitates IL-15 Production and T Cell Maintenance Following Allergic Hypersensitivity Responses ,null, Frontiers in Immunology ,PubMed ID 34659203
Replication gaps are a key determinant of PARP inhibitor synthetic lethality with BRCA deficiency ,null, Molecular cell ,PubMed ID 34216544
Synergistic effects of FGFR1 and PLK1 inhibitors target a metabolic liability in KRAS‐mutant cancer ,null, EMBO Molecular Medicine ,PubMed ID 34369083
Co-Stimulation of Oxytocin and Arginine-Vasopressin Receptors Affect Hypothalamic Neurospheroid Size ,null, International Journal of Molecular Sciences ,PubMed ID 34445168
Complement receptor 3 mediates Aspergillus fumigatus internalization into alveolar epithelial cells with the increase of intracellular phosphatidic acid by activating FAK ,null, Virulence ,PubMed ID 34338598
Targeting HIF-activated collagen prolyl 4-hydroxylase expression disrupts collagen deposition and blocks primary and metastatic uveal melanoma growth ,null, Oncogene ,PubMed ID 34218269
Sodium bicarbonate transporter NBCe1 regulates proliferation and viability of human prostate cancer cells LNCaP and PC3 ,Li, JM;Lee, S;Zafar, R;Shin, E;Choi, I;, Oncology reports ,PubMed ID 34013380 [Scrambled Control ]
HIGD-1B inhibits hypoxia-induced mitochondrial fragmentation by regulating OPA1 cleavage in cardiomyocytes ,null, Molecular Medicine Reports ,PubMed ID 34080026
Characterization of the Inducible and Slow-Releasing Hydrogen Sulfide and Persulfide Donor P*: Insights into Hydrogen Sulfide Signaling ,null, Antioxidants ,PubMed ID 34209813
TRPM7 kinase-mediated immunomodulation in macrophage plays a central role in magnesium ion-induced bone regeneration ,null, Nature Communications ,PubMed ID 34001887
PARP1 Is Targeted by miR-519a-3p and Promotes the Migration, Invasion, and Tube Formation of Ovarian Cancer Cells ,Chang, H;Zhang, X;Li, B;Meng, X;, Cancer biotherapy & radiopharmaceuticals ,PubMed ID 34009012 [Scrambled Control ]
N-cadherin mediates the migration of bone marrow-derived mesenchymal stem cells toward breast tumor cells ,Choi, S;Yu, J;Kim, W;Park, KS;, Theranostics ,PubMed ID 34093853 [Scrambled Control]
Dihydrolipoic acid enhances autophagy and alleviates neurological deficits after subarachnoid hemorrhage in rats ,Zhou, K;Enkhjargal, B;Mo, J;Zhang, T;Zhu, Q;Wu, P;Reis, C;Tang, J;Zhang, JH;Zhang, J;, Experimental neurology ,PubMed ID 33974879 [Scrambled Control ]
RIPK1 is a negative mediator in Aquaporin 1-driven triple-negative breast carcinoma progression and metastasis ,Yin, Z;Chen, W;Yin, J;Sun, J;Xie, Q;Wu, M;Zeng, F;Ren, H;, NPJ breast cancer ,PubMed ID 33980862 [Scrambled Control ]
Administration of quercetin improves mitochondria quality control and protects the neurons in 6-OHDA-lesioned Parkinson\'s disease models ,Wang, WW;Han, R;He, HJ;Li, J;Chen, SY;Gu, Y;Xie, C;, Aging ,PubMed ID 33878030 [Scrambled Control ]
Human colorectal cancer-associated carbohydrate antigen on annexin A2 protein ,Tanaka, H;Saigo, C;Iwata, Y;Yasufuku, I;Kito, Y;Yoshida, K;Takeuchi, T;, Journal of molecular medicine (Berlin, Germany) 2021 ,PubMed ID 33904933 [Scrambled Control]
Discovery and Pharmacological Evaluation of STEAP4 as a Novel Target for HER2 Overexpressing Breast Cancer ,null, Frontiers in Oncology ,PubMed ID 33842315
Pharmacological Inhibition of Brain EGFR Activation By a BBB-penetrating Inhibitor, AZD3759, Attenuates α-synuclein Pathology in a Mouse Model of α-Synuclein Propagation ,Tavassoly, O;Del Cid Pellitero, E;Larroquette, F;Cai, E;Thomas, RA;Soubannier, V;Luo, W;Durcan, TM;Fon, EA;, Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics ,PubMed ID 33713002 [Scrambled Control]
Promoting effects of MiR-135b on human multiple myeloma cells via regulation of the Wnt/β-catenin/Versican signaling pathway ,Chen, H;Zhao, Y;Zhang, J;Xie, Y;Jin, M;, Cytokine ,PubMed ID 33765653 [Negative Control]
Human METTL7B is an alkyl thiol methyltransferase that metabolizes hydrogen sulfide and captopril ,Maldonato, BJ;Russell, DA;Totah, RA;, Scientific reports ,PubMed ID 33649426 [Scrambled Control]
MiR-205 Promotes the Viability, Migration, and Tube Formation of Cervical Cancer Cells In Vitro by Targeting GATA3 ,Han, H;Xu, X;, Cancer biotherapy & radiopharmaceuticals ,PubMed ID 33784470 [Scrambled Control]
The MicroRNA miR-696 is Regulated by SNARK and Reduces Mitochondrial Activity in Mouse Skeletal Muscle Through Pgc1α Inhibition ,Queiroz, A;Lessard, S;Ouchida, A;Araujo, H;Gon?alves, D;Sim?es Fr?es Guimar?es, D;Teodoro, B;So, K;Espreafico, E;Hirshman, M;Alberici, L;Kettelhut, I;Goodyear, L;Silveira, L;, Molecular Metabolism ,PubMed ID 33812060 [Scrambled Control]
E3 ubiquitin ligase RNF126 affects bladder cancer progression through regulation of PTEN stability ,Xu, H;Ju, L;Xiong, Y;Yu, M;Zhou, F;Qian, K;Wang, G;Xiao, Y;Wang, X;, Cell death & disease ,PubMed ID 33664240 [Scrambled Control]
Mesenchymal stem cell-derived interleukin-28 drives the selection of apoptosis resistant bone metastatic prostate cancer ,McGuire, JJ;Frieling, JS;Lo, CH;Li, T;Muhammad, A;Lawrence, HR;Lawrence, NJ;Cook, LM;Lynch, CC;, Nature communications ,PubMed ID 33526787 [Scrambled Control]
WHSC1/NSD2 regulates immune infiltration in prostate cancer ,Want, MY;Tsuji, T;Singh, PK;Thorne, JL;Matsuzaki, J;Karasik, E;Gillard, B;Cortes Gomez, E;Koya, RC;Lugade, A;Odunsi, K;Battaglia, S;, Journal for immunotherapy of cancer ,PubMed ID 33589522 [Scrambled Control]
Angiotensin II-Induced Histone Deacetylase 5 Phosphorylation, Nuclear Export and Egr-1 Expression is mediated by Akt Pathway in A10 Vascular Smooth Muscle Cells ,Truong, V;Jain, A;Anand-Srivastava, MB;Srivastava, AK;, American journal of physiology. Heart and circulatory physiology ,PubMed ID 33606583 [Scrambled Control]
Efficient Ocular Delivery of VCP siRNA via Reverse Magnetofection in RHO P23H Rodent Retina Explants ,Sen, M;Bassetto, M;Poulhes, F;Zelphati, O;Ueffing, M;Arango-Gonzalez, B;, Pharmaceutics ,PubMed ID 33562020 [Scrambled Control]
ErbB3 is a critical regulator of cytoskeletal dynamics in brain microvascular endothelial cells: Implications for vascular remodeling and blood-brain-barrier modulation ,Wu, L;Islam, MR;Lee, J;Takase, H;Guo, S;Andrews, AM;Buzhdygan, TP;Mathew, J;Li, W;Arai, K;Lo, EH;Ramirez, SH;Lok, J;, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism ,PubMed ID 33583260 [Scrambled Control]
Therapeutic potential of targeting HSPA5 through dual regulation of two candidate prognostic biomarkers ANXA1 and PSAT1 in osteosarcoma ,null, Aging (Albany NY) ,PubMed ID 33291071
Antitumor Activity of Asperphenin B by Induction of Apoptosis and Regulation of Glyceraldehyde-3-phosphate Dehydrogenase in Human Colorectal Cancer Cells ,null, Journal of Natural Products ,PubMed ID 33398999
The harsh microenvironment in early breast cancer selects for a Warburg phenotype ,null, Proceedings of the National Academy of Sciences of the United States of America ,PubMed ID 33452133
SIRPα Suppresses Response to Therapeutic Antibodies by Nurse Like Cells From Chronic Lymphocytic Leukemia Patients ,null, Frontiers in Immunology ,PubMed ID 33552071
The calcium-activated chloride channel-associated protein rCLCA2 is expressed throughout rat epidermis, facilitates apoptosis and is downmodulated by UVB ,Hämäläinen, L;Bart, G;Takabe, P;Rauhala, L;Deen, A;Pasonen-Seppänen, S;Kärkkäinen, E;Kärnä, R;Kumlin, T;Tammi, MI;Tammi, RH;, Histochemistry and cell biology ,PubMed ID 33486586 [Scrambled Control]
The translocon-associated protein (TRAP) complex regulates quality control of N-linked glycosylation during ER stress ,Phoomak, C;Cui, W;Hayman, TJ;Yu, SH;Zhao, P;Wells, L;Steet, R;Contessa, JN;, Science Advances ,PubMed ID 33523898 [Scrambled Control]
Growth Hormone Upregulates Mediators of Melanoma Drug Efflux and Epithelial-to-Mesenchymal Transition In Vitro and In Vivo ,Qian, Y;Basu, R;Mathes, SC;Arnett, NA;Duran-Ortiz, S;Funk, KR;Brittain, AL;Kulkarni, P;Terry, JC;Davis, E;Singerman, JT;Henry, BE;List, EO;Berryman, DE;Kopchick, JJ;, Cancers ,PubMed ID 33291663 [Scrambled Control]
Autophagy alleviates hypoxia-induced blood-brain barrier injury via regulation of CLDN5 (claudin 5) ,Yang, Z;Lin, P;Chen, B;Zhang, X;Xiao, W;Wu, S;Huang, C;Feng, D;Zhang, W;Zhang, J;, Autophagy ,PubMed ID 33280500 [Scrambled Control]
Facilitation of Bone Healing Processes Based on the Developmental Function of Meox2 in Tooth Loss Lesion ,null, International Journal of Molecular Sciences ,PubMed ID 33218046
Developmental Roles of FUSE Binding Protein 1 (Fubp1) in Tooth Morphogenesis ,null, International Journal of Molecular Sciences ,PubMed ID 33138041
Activation of RAS Signalling is Associated with Altered Cell Adhesion in Phaeochromocytoma ,null, International Journal of Molecular Sciences ,PubMed ID 33138083
iTRAQ‑based proteomic analysis of the interaction of A549 human lung epithelial cells with Aspergillus fumigatus conidia ,Zhang, X;He, D;Gao, S;Wei, Y;Wang, L;Zhang, X;He, D;Gao, S;Wei, Y;Wang, L;Zhang, X;He, D;Gao, S;Wei, Y;Wang, L;Zhang, X;He, D;Gao, S;Wei, Y;Wang, L;Zhang, X;He, D;Gao, S;Wei, Y;Wang, L;, Mol Med Rep ,PubMed ID 33174000 [CONTROL VECTOR]
Occludin, caveolin‐1, and Alix form a multi‐protein complex and regulate HIV‐1 infection of brain pericytes ,null, The FASEB Journal ,PubMed ID 33058236
Down-regulating miR-217-5p Protects Cardiomyocytes against Ischemia/Reperfusion Injury by Restoring Mitochondrial Function via Targeting SIRT1 ,Qi, Y;Zhang, K;Li, P;Wu, Z;, Inflammation ,PubMed ID 33064238 [Negative Control]
Stearic Acid and TNF-α Co-Operatively Potentiate MIP-1α Production in Monocytic Cells via MyD88 Independent TLR4/TBK/IRF3 Signaling Pathway ,Kochumon, S;Arefanian, H;Azim, R;Shenouda, S;Jacob, T;Abu Khalaf, N;Al-Rashed, F;Hasan, A;Sindhu, S;Al-Mulla, F;Ahmad, R;, Biomedicines ,PubMed ID 33050324 [Negative Control]
TIMP-2 regulates proliferation, invasion and STAT3-mediated cancer stem cell-dependent chemoresistance in ovarian cancer cells ,null, BMC Cancer ,PubMed ID 33023532
Palmitate-induced IRE1-XBP1-ZEB signaling represses desmoplakin expression and promotes cancer cell migration ,null, Molecular cancer research : MCR ,PubMed ID 33106375
miR‑589‑3p sponged by the lncRNA TINCR inhibits the proliferation, migration and invasion and promotes the apoptosis of breast cancer cells by suppressing the Akt pathway via IGF1R ,Guo, F;Zhu, X;Zhao, Q;Huang, Q;, Int. J. Mol. Med. ,PubMed ID 32705168 [ACP1]
MRP5 nitration by NO-releasing gemcitabine encapsulated in liposomes confers sensitivity in chemoresistant pancreatic adenocarcinoma cells ,Masetto, F;Chegaev, K;Gazzano, E;Mullappilly, N;Rolando, B;Arpicco, S;Fruttero, R;Riganti, C;Donadelli, M;, Biochim Biophys Acta Mol Cell Res ,PubMed ID 32828758 [ACP1]
Modulation of Human Arylamine N -Acetyltransferase 1 Activity by Lysine Acetylation: Role of p300/CREB-Binding Protein and Sirtuins 1 and 2. ,null, Molecular pharmacology ,PubMed ID 32487734
Osthole interacts with an ER-mitochondria axis and facilitates tumor suppression in ovarian cancer ,Bae, H;Lee, JY;Song, J;Song, G;Lim, W;, J. Cell. Physiol. ,PubMed ID 32697363 [ACP1]
Geometric regulation of histone state directs melanoma reprogramming ,Lee, J;Molley, TG;Seward, CH;Abdeen, AA;Zhang, H;Wang, X;Gandhi, H;Yang, JL;Gaus, K;Kilian, KA;, Commun Biol ,PubMed ID 32620903 [Negative Control]
Molecular characterization of the calcium release channel deficiency syndrome ,Tester, DJ;Kim, CSJ;Hamrick, SK;Ye, D;O'Hare, BJ;Bombei, HM;Fitzgerald, KK;Haglund-Turnquist, CM;Atkins, DL;Ochoa Nunez, LA;Law, IH;Temple, JD;Ackerman, MJ;, JCI Insight ,PubMed ID 32663189 [Negative Control]
Protein phosphatase 1 catalyzes HBV core protein dephosphorylation and is co-packaged with viral pregenomic RNA into nucleocapsids ,null, PLoS Pathogens ,PubMed ID 32702076
Role of FOXM1 in vascular smooth muscle cell survival and neointima formation following vascular injury ,Franco, S;Stranz, A;Ljumani, F;Urabe, G;Chaudhary, M;Stewart, D;Pilli, VS;Kelly, M;Yamanouchi, D;Kent, KC;Liu, B;, Heliyon ,PubMed ID 32577545 [Negative Control]
Eupatilin Promotes Cell Death by Calcium Influx through ER-Mitochondria Axis with SERPINB11 Inhibition in Epithelial Ovarian Cancer ,Lee, JY;Bae, H;Yang, C;Park, S;Youn, BS;Kim, HS;Song, G;Lim, W;, Cancers (Basel) 2020 ,PubMed ID 32503295 [Scrambles Control]
Transcription factor AP2A affects sFLT1 expression and decidualization in decidual stromal cells: Implications to preeclampsia pathology. ,null, Pregnancy hypertension ,PubMed ID 32535226
Melatonin improves uterine-conceptus interaction via regulation of SIRT1 during early pregnancy ,Bae, H;Yang, C;Lee, JY;Park, S;Bazer, FW;Song, G;Lim, W;, J. Pineal Res. ,PubMed ID 32421880 [Negative Control]
FAM110B Inhibits Non-Small Cell Lung Cancer Cell Proliferation and Invasion Through Inactivating Wnt/β-Catenin Signaling ,Xie, M;Cai, L;Li, J;Zhao, J;Guo, Y;Hou, Z;, OncoTargets and Therapy ,PubMed ID 32547070 [Negative Control]
A miR-494 dependent feedback loop regulates ER stress ,Chatterjee, N;Espinosa-Diez, C;Anand, S;, bioRxiv [Scrambled Control]
TRAF3IP3 negatively regulates cytosolic RNA induced anti-viral signaling by promoting TBK1 K48 ubiquitination ,Deng, M;Tam, JW;Wang, L;Liang, K;Li, S;Zhang, L;Guo, H;Luo, X;Zhang, Y;Petrucelli, A;Davis, BK;Conti, BJ;June Brickey, W;Ko, CC;Lei, YL;Sun, S;Ting, JP;, Nat Commun ,PubMed ID 32366851 [Negative Control]
Aberrant expression of CPSF1 promotes head and neck squamous cell carcinoma via regulating alternative splicing ,null, PLoS ONE ,PubMed ID 32437477
The Harsh Microenvironment in Early Breast Cancer Selects for a Warburg Phenotype ,Damaghi, M;West, J;Robertson-Tessi, M;Xu, L;, bioRxiv [Negative Control]
Prohibitin 1/2 mediates Dengue-3 entry into human neuroblastoma (SH-SY5Y) and microglia (CHME-3) cells ,Sharma, A;Vasanthapuram, R;M Venkataswamy, M;Desai, A;, J. Biomed. Sci. ,PubMed ID 32306962 [Negative Control]
Arachidonate 12-Lipoxygenase and 12-Hydroxyeicosatetraenoic acid contribute to stromal aging-induced progression of pancreatic cancer ,Sarsour, EH;Son, JM;Kalen, AL;Xiao, W;Du, J;Alexander, MS;O'Leary, BR;Cullen, JJ;Goswami, PC;, J. Biol. Chem. ,PubMed ID 32265301 [Negative Control]
Myo-Inositol Oxygenase (MIOX) Overexpression Drives the Progression of Renal Tubulo-Interstitial Injury in Diabetes ,Sharma, I;Deng, F;Liao, Y;Kanwar, YS;, Diabetes ,PubMed ID 32169892 [Negative Control]
(-)-Epigallocatechin gallate inhibits stemness and tumourigenicity stimulated by AXL receptor tyrosine kinase in human lung cancer cells ,Namiki, K;Wongsirisin, P;Yokoyama, S;Sato, M;Rawangkan, A;Sakai, R;Iida, K;Suganuma, M;, Sci Rep ,PubMed ID 32051483 [negative Control]
Ezetimibe Attenuates Oxidative Stress and Neuroinflammation via the AMPK/Nrf2/TXNIP Pathway after MCAO in Rats ,Yu, J;Wang, WN;Matei, N;Li, X;Pang, JW;Mo, J;Chen, SP;Tang, JP;Yan, M;Zhang, JH;, Oxid Med Cell Longev ,PubMed ID 31998437 [ACP1]
Upregulation of the Coatomer Protein Complex Subunit beta 2 (COPB2) Gene Targets microRNA-335-3p in NCI-H1975 Lung Adenocarcinoma Cells to Promote Cell Proliferation and Migration ,Pu, X;Jiang, H;Li, W;Xu, L;Wang, L;Shu, Y;, Med. Sci. Monit. ,PubMed ID 32004259 [Negative Control]
PARP1 enhances influenza A virus propagation by facilitating degradation of host type I interferon receptor ,Xia, C;Wolf, JJ;Sun, C;Xu, M;Studstill, CJ;Chen, J;Ngo, H;Zhu, H;Hahm, B;, J. Virol. ,PubMed ID 31915279 [Negative Control]
Autophagy inhibition blunts PDGFRA adipose progenitors\' cell-autonomous fibrogenic response to high-fat diet ,Marcelin, G;Da Cunha, C;Gamblin, C;Suffee, N;Rouault, C;Leclerc, A;Lacombe, A;Sokolovska, N;Gautier, EL;Clément, K;Dugail, I;, Autophagy ,PubMed ID 31992125 [Negative Control]
YAP-dependent necrosis occurs in early stages of Alzheimer\'s disease and regulates mouse model pathology ,Tanaka, H;Homma, H;Fujita, K;Kondo, K;Yamada, S;Jin, X;Waragai, M;Ohtomo, G;Iwata, A;Tagawa, K;Atsuta, N;Katsuno, M;Tomita, N;Furukawa, K;Saito, Y;Saito, T;Ichise, A;Shibata, S;Arai, H;Saido, T;Sudol, M;Muramatsu, SI;Okano, H;Mufson, EJ;Sobue, G;Murayama, S;Okazawa, H;, Nat Commun ,PubMed ID 31980612 [Negative Control]
Copy number gains of the putative CRKL oncogene in laryngeal squamous cell carcinoma result in strong nuclear expression of the protein and influence cell proliferation and migration ,null, Scientific Reports ,PubMed ID 31913340
Chronic morphine-mediated upregulation of high mobility group box 1 in the spinal cord contributes to analgesic tolerance and hyperalgesia in rats ,Qian, J;Zhu, Y;Bai, L;Gao, Y;Jiang, M;Xing, F;Zhang, J;Zhao, W;Gu, H;Mi, Y;Tao, YX;Xu, JT;, Neurotherapeutics ,PubMed ID 31879851 [Scrambled Control]
Geometric regulation of histone state directs melanoma reprogramming ,Lee, J;Molley, TG;Seward, CH;Abdeen, AA;Zhang, H;, bioRxiv [Negative Control]
CD36-Mediated Metabolic Rewiring of Breast Cancer Cells Promotes Resistance to HER2-Targeted Therapies ,Feng, WW;Wilkins, O;Bang, S;Ung, M;Li, J;An, J;Del Genio, C;Canfield, K;DiRenzo, J;Wells, W;Gaur, A;Robey, RB;Guo, JY;Powles, RL;Sotiriou, C;Pusztai, L;Febbraio, M;Cheng, C;Kinlaw, WB;Kurokawa, M;, Cell Rep ,PubMed ID 31825825 [Scrambled Control]
STK3/4 Expression Is Regulated in Uterine Endometrial Cells during the Estrous Cycle ,Moon, S;Lee, OH;Lee, S;Lee, J;Park, H;Park, M;Chang, EM;Park, KH;Choi, Y;, Cells ,PubMed ID 31847471 [Scrambled Control]
Myricetin inhibits Endometriosis growth through Cyclin E1 Downregulation In Vitro and In Vivo ,Park, S;Song, G;Lim, W;, The Journal of Nutritional Biochemistry ,PubMed ID 31952013 [Negative Control]
HAS3-induced extracellular vesicles from melanoma cells stimulate IHH mediated c-Myc upregulation via the hedgehog signaling pathway in target cells ,null, Cellular and Molecular Life Sciences ,PubMed ID 31820036
Estrogenic and anti-inflammatory effects of pseudoprotodioscin in atherosclerosis-prone mice: Insights into endothelial cells and perivascular adipose tissues. ,null, European journal of pharmacology ,PubMed ID 31877277
Fam20C‐mediated phosphorylation of osteopontin is critical for its secretion but dispensable for its action as a cytokine in the activation of hepatic stellate cells in liver fibrogenesis ,Tibaldi, E;Brocca, A;Sticca, A;Gola, E;Pizzi, M;Bordin, L;Pagano, M;Mazzorana, M;Donà, G;Violi, P;Marin, O;Romano, A;Angeli, P;Carraro, A;Brunati, A;, FASEB j. ,PubMed ID 31914633 [Negative Control]
PTPRS drives adaptive resistance to MEK/ERK inhibitors through SRC ,Davis, TB;Yang, M;Wang, H;Lee, C;Yeatman, TJ;Pledger, WJ;, Oncotarget ,PubMed ID 31827720 [Negative Control]
RELA is sufficient to mediate interleukin-1 repression of androgen receptor expression and activity in an LNCaP disease progression model ,null, The Prostate ,PubMed ID 31730277
IL-27 posttranslationally regulates Y-box binding protein-1 to inhibit HIV-1 replication in human CD4+ T cells ,Poudyal, D;Yang, J;Chen, Q;Goswami, S;Adelsberger, JW;Das, S;Herman, A;Hornung, RL;Andresson, T;Imamichi, T;, AIDS ,PubMed ID 31274540 [Negative Control]
Proximity Labeling To Map Host-Pathogen Interactions at the Membrane of a Bacterium-Containing Vacuole in Chlamydia trachomatis-Infected Human Cells ,null, Infection and Immunity ,PubMed ID 31405957
EZH2 targeting in medulloblastoma reduces tumor growth through epigenetic reactivation of the BAI1/p53 tumor suppressor pathway ,null, Oncogene ,PubMed ID 31582835
Components of genetic associations across 2,138 phenotypes in the UK Biobank highlight adipocyte biology ,Tanigawa, Y;Li, J;Justesen, JM;Horn, H;Aguirre, M;DeBoever, C;Chang, C;Narasimhan, B;Lage, K;Hastie, T;Park, CY;Bejerano, G;Ingelsson, E;Rivas, MA;, Nat Commun ,PubMed ID 31492854 [Negative Control]
Interleukin 21 Receptor/Ligand Interaction Is Linked to Disease Progression in Pancreatic Cancer ,Linnebacher, A;Mayer, P;Marnet, N;Bergmann, F;Herpel, E;Revia, S;Yin, L;Liu, L;Hackert, T;Giese, T;Herr, I;Gaida, MM;, Cells ,PubMed ID 31540511 [ACP1]
Prostate tumor cell-derived IL-1β induces an inflammatory phenotype in bone marrow adipocytes and reduces sensitivity to docetaxel via lipolysis-dependent mechanisms ,Herroon, MK;Diedrich, JD;Rajagurubandara, E;Martin, C;Maddipati, K;Kim, S;Heath, EI;Granneman, J;Podgorski, I;, Mol. Cancer Res. ,PubMed ID 31562254 [Negative Control]
RELA is Sufficient to Mediate Interleukin-1 (IL-1) Repression of Androgen Receptor Expression and Activity in LNCaP Disease Progression Model ,Thomas-Jardin, S;Dahl, H;Kanchwala, M;Ha, F;Jacob, J;, bioRxiv [Negative Control]
PARPi synthetic lethality derives from replication-associated single-stranded DNA gaps ,Cong, K;Kousholt, AN;Peng, M;Panzarino, NJ;Lee, WTC;, bioRxiv [Negative Control]
HELLS and PRDM9 form a Pioneer Complex to Open Chromatin at Meiotic Recombination Hotspots ,Spruce, C;Dlamini, S;Ananda, G;Bronkema, N;Tian, H;, bioRxiv [Negative Control]
MicroRNA-519c-3p promotes tumor growth and metastasis of hepatocellular carcinoma by targeting BTG3 ,Wang, L;Mo, H;Jiang, Y;Wang, Y;Sun, L;Yao, B;Chen, T;Liu, R;Li, Q;Liu, Q;Yin, G;, Biomed. Pharmacother. ,PubMed ID 31387005 [Negative Control]
COPB2 promotes metastasis and inhibits apoptosis of lung adenocarcinoma cells through functioning as a target of miR-216a-3p ,null, Translational Cancer Research ,PubMed ID 35117624
SGPL1321 mutation: one main trigger for invasiveness of pediatric alveolar rhabdomyosarcoma ,Adamus, A;Engel, N;Seitz, G;, Cancer Gene Ther. ,PubMed ID 31455837 [Negative Control]
Glutamine Metabolism Drives Growth in Advanced Hormone Receptor Positive Breast Cancer ,null, Frontiers in Oncology ,PubMed ID 31428575
Physiological roles of the GIP receptor in murine brown adipose tissue ,null, Molecular Metabolism ,PubMed ID 31451430
FAM163A, a positive regulator of ERK signaling pathway, interacts with 14-3-3β and promotes cell proliferation in squamous cell lung carcinoma ,Liu, N;Zhou, H;Zhang, X;Cai, L;Li, J;Zhao, J;Liu, Y;Wang, L;Fan, C;Li, A;Miao, Y;, Onco Targets Ther ,PubMed ID 31496741 [Negative Control]
TNF-α in Combination with Palmitate Enhances IL-8 Production via The MyD88- Independent TLR4 Signaling Pathway: Potential Relevance to Metabolic Inflammation ,Hasan, A;Akhter, N;Al-Roub, A;Thomas, R;Kochumon, S;Wilson, A;Koshy, M;Al-Ozairi, E;Al-Mulla, F;Ahmad, R;, Int J Mol Sci ,PubMed ID 31443599 [Negative Control]
Knockdown Rab11-FIP2 inhibits migration and invasion of nasopharyngeal carcinoma via suppressing Rho GTPase signaling ,Feng, G;Qin, L;Liao, Z;Xiao, X;Li, B;Cui, W;Liang, L;Mo, Y;Huang, G;Li, P;Zhou, X;Zhang, Z;Xiao, X;, J. Cell. Biochem. ,PubMed ID 31452257 [Negative Control]
Characterization of the polarized endothelial secretome. ,null, FASEB journal : official publication of the Federation of American Societies for Experimental Biology ,PubMed ID 31431053
Macrophage migration inhibitory factor-CD74 interaction regulates the expression of programmed cell death ligand 1 in melanoma cells ,Imaoka, M;Tanese, K;Masugi, Y;Hayashi, M;Sakamoto, M;, Cancer Sci. ,PubMed ID 31069878 [Negative Control]
E2F1 activates MFN2 expression by binding to the promoter and decreases mitochondrial fission and mitophagy in HeLa cells ,Bucha, S;Mukhopadhyay, D;Bhattacharyya, NP;, FEBS J. ,PubMed ID 31276298 [Negative Control]
FGF-2 Attenuates Neuronal Apoptosis via FGFR3/PI3k/Akt Signaling Pathway After Subarachnoid Hemorrhage ,Okada, T;Enkhjargal, B;Travis, ZD;Ocak, U;Tang, J;Suzuki, H;Zhang, JH;, Mol. Neurobiol. ,PubMed ID 31203572 [Negative Control]
Menin Associates with the Mitotic Spindle and is Important for Cell Division ,Sawicki, MP;Gholkar, AA;Torres, JZ;, Endocrinology ,PubMed ID 31211356 [Negative Control]
Effect of haptoglobin on the treatment of chronic hepatitis B with interferon ,Lv, L;Yang, Y;Shi, T;, Exp Ther Med ,PubMed ID 31316628 [Negative Control]
miR-3691-5p promotes hepatocellular carcinoma cell migration and invasion through activating PI3K/Akt signaling by targeting PTEN ,Du, W;Zhang, X;Wan, Z;, Onco Targets Ther ,PubMed ID 31417285 [Negative Control]
INPP4B exerts a dual function in the stemness of colorectal cancer stem-like cells through regulating Sox2 and Nanog expression ,Yang, L;Ding, C;Tang, W;Yang, T;Liu, M;Wu, H;Wen, K;Yao, X;Feng, J;Luo, J;, Carcinogenesis ,PubMed ID 31179504 [Negative Control]
MZF1 and SCAND1 Reciprocally Regulate CDC37 Gene Expression in Prostate Cancer ,null, Cancers ,PubMed ID 31181782
Role for polo-like kinase 4 in mediation of cytokinesis ,Press, MF;Xie, B;Davenport, S;Zhou, Y;Guzman, R;Nolan, GP;O'Brien, N;Palazzolo, M;Mak, TW;Brugge, JS;Slamon, DJ;, Proc. Natl. Acad. Sci. U.S.A. ,PubMed ID 31097597 [Scrambled Control]
Involvement of Akt-dependent CREB signaling pathway in hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>)-induced early growth response protein-1 (Egr-1) expression in vascular smooth muscle cells ,Rondeau, V;Jain, A;Truong, V;Srivastava, AK;, Can. J. Physiol. Pharmacol. ,PubMed ID 30939252 [Negative Control]
Metabolic and Innate Immune Cues Merge into a Specific Inflammatory Response via the UPR ,Mogilenko, DA;Haas, JT;L'homme, L;Fleury, S;Quemener, S;Levavasseur, M;Becquart, C;Wartelle, J;Bogomolova, A;Pineau, L;Molendi-Coste, O;Lancel, S;Dehondt, H;Gheeraert, C;Melchior, A;Dewas, C;Nikitin, A;Pic, S;Rabhi, N;Annicotte, JS;Oyadomari, S;Velasco-Hernandez, T;Cammenga, J;Foretz, M;Viollet, B;Vukovic, M;Villacreces, A;Kranc, K;Carmeliet, P;Marot, G;Boulter, A;Tavernier, S;Berod, L;Longhi, MP;Paget, C;Janssens, S;Staumont-Sallé, D;Aksoy, E;Staels, B;Dombrowicz, D;, Cell ,PubMed ID 31031005 [Negative Control]
MicroRNA‑214 upregulates HIF‑1α and VEGF by targeting ING4 in lung cancer cells ,Li, Y;Zhao, L;Qi, Y;Yang, X;, Mol Med Report ,PubMed ID 31059086 [Negative Control]
Immunoglobulin light chains generate pro-inflammatory and pro-fibrotic kidney injury ,Ying, W;Li, X;Rangarajan, S;Feng, W;Curtis, L;Sanders, P;, Journal of Clinical Investigation ,PubMed ID 31205024 [Negative Control]
CACNA2D3 Enhances the Chemosensitivity of Esophageal Squamous Cell Carcinoma to Cisplatin via Inducing Ca2+-Mediated Apoptosis and Suppressing PI3K/Akt Pathways ,Nie, C;Qin, X;Li, X;Tian, B;Zhao, Y;Jin, Y;Li, Y;Wang, Q;Zeng, D;Hong, A;Chen, X;, Front Oncol ,PubMed ID 31001468 [Negative Control]
An endoplasmic reticulum stress regulator, Tmbim6, modulates secretory stage of mice molar ,Aryal, YP;Neupane, S;Adhikari, N;An, CH;Ha, JH;Kwon, TY;Yamamoto, H;Jung, JK;Park, EK;Kim, JY;Cho, SW;Sohn, WJ;Lee, Y;Chae, HJ;Kim, HR;Kim, JY;, J. Cell. Physiol. ,PubMed ID 30963569 [Negative Control]
Protein kinase D1 induces G1-phase cell-cycle arrest independent of Checkpoint kinases by phosphorylating Cell Division Cycle Phosphatase 25 ,null, The Prostate ,PubMed ID 30958903
Cell cycle genes are downregulated after adipogenic triggering in human adipose tissue-derived stem cells by regulation of mRNA abundance ,null, Scientific Reports ,PubMed ID 30948750
Ameliorative effects of luteolin against endometriosis progression in vitro and in vivo ,Park, S;Lim, W;You, S;Song, G;, J. Nutr. Biochem. ,PubMed ID 30925413 [Negative Control]
Oncogenic properties of the antisense lncRNA COMET in BRAF- and RET-driven papillary thyroid carcinomas ,Esposito, R;Esposito, D;Ciccodicola, A;Costa, V;, Cancer Res. ,PubMed ID 30862713 [Negative Control]
Protein kinase B mediates insulin-like growth factor 1-induced phosphorylation and nuclear export of histone deacetylase 5 via NADPH oxidase 4 activation in vascular smooth muscle cells ,Pietruczuk, P;Jain, A;Simo-Cheyou, ER;Anand-Srivastava, MB;Srivastava, AK;, J. Cell. Physiol. ,PubMed ID 30793765 [Negative Control]
Nkx2-5 Second Heart Field Target Gene Ccdc117 Regulates DNA Metabolism and Proliferation ,Horton, AJ;Brooker, J;Streitfeld, WS;Flessa, ME;Pillai, B;Simpson, R;Clark, CD;Gooz, MB;Sutton, KK;Foley, AC;Lee, KH;, Sci Rep ,PubMed ID 30742009 [Negative Control]
Nuclear localization of LDL receptor-related protein 1B in mammary gland carcinogenesis ,Asano, Y;Takeuchi, T;Okubo, H;Saigo, C;Kito, Y;Iwata, Y;Futamura, M;Yoshida, K;, J. Mol. Med. ,PubMed ID 30607440 [Scrambled Control]
MicroRNA-101 inhibits cell migration and invasion in bladder cancer via targeting FZD4 ,Chen, L;Long, Y;Han, Z;Yuan, Z;Liu, W;Yang, F;Li, T;Shu, L;Zhong, Y;, Exp Ther Med ,PubMed ID 30680031 [Scrambled Control]
The brown adipose tissue glucagon receptor is functional but not essential for control of energy homeostasis in mice ,Beaudry, JL;Kaur, KD;Varin, EM;Baggio, LL;Cao, X;Mulvihill, EE;Stern, JH;Campbell, JE;Scherer, PE;Drucker, DJ;, Mol Metab ,PubMed ID 30772257 [Negative Control]
Avobenzone suppresses proliferative activity of human trophoblast cells and induces apoptosis mediated by mitochondrial disruption. ,null, Reproductive toxicology (Elmsford, N.Y.) ,PubMed ID 29981360
4-Methylbenzylidene-camphor inhibits proliferation and induces reactive oxygen species-mediated apoptosis of human trophoblast cells ,Yang, C;Lim, W;You, S;Song, G;, Reprod. Toxicol. ,PubMed ID 30597193 [Negative Control]
Upregulation of Ets1 expression by NFATc2 and NFKB1/RELA promotes breast cancer cell invasiveness ,Kim, GC;Kwon, HK;Lee, CG;Verma, R;Rudra, D;Kim, T;Kang, K;Nam, JH;Kim, Y;Im, SH;, Oncogenesis ,PubMed ID 30467308 [Negative Control]
Increasing intratumor C/EBP-β LIP and nitric oxide levels overcome resistance to doxorubicin in triple negative breast cancer ,Salaroglio, IC;Gazzano, E;Abdullrahman, A;Mungo, E;Castella, B;Abd-Elrahman, GEFA;Massaia, M;Donadelli, M;Rubinstein, M;Riganti, C;Kopecka, J;, J. Exp. Clin. Cancer Res. ,PubMed ID 30482226 [ACP1]
Macrophage Stimulating Protein (MSP) Preserves Blood Brain Barrier Integrity After Intracerebral Hemorrhage Through RON Dependent GAB1/Src/β-catenin Pathway Activation in a Mouse Model ,Lu, T;Wang, Z;Prativa, S;Xu, Y;Wang, T;Zhang, Y;Yu, L;Xu, N;Tang, J;You, W;Chen, G;Zhang, JH;, J. Neurochem. ,PubMed ID 30380151 [Negative Control]
Activated kinase screening identifies the IKBKE oncogene as a positive regulator of autophagy ,Leonardi, M;Perna, E;Tronnolone, S;Colecchia, D;Chiariello, M;, Autophagy ,PubMed ID 30289335 [Negative Control]
Quercetin inhibits proliferation of endometriosis regulating cyclin D1 and its target microRNAs in vitro and in vivo ,Park, S;Lim, W;Bazer, FW;Whang, KY;Song, G;, J. Nutr. Biochem. ,PubMed ID 30359864 [Negative Control]
Components of genetic associations across 2,138 phenotypes in the UK Biobank highlight novel adipocyte biology ,Tanigawa, Y;Li, J;Justesen, J;Horn, H;Aguirre, M;DeBoever, C;Chang, C;Narasimhan, B;Lage, K;Hastie, T;Park, C;Bejerano, G;Ingelsson, E;Rivas, M;, bioRxiv [Negative Control]
Curcumin analog, GO-Y078, overcomes resistance to tumor angiogenesis inhibitors ,Shimazu, K;Inoue, M;Sugiyama, S;Fukuda, K;Yoshida, T;Taguchi, D;Uehara, Y;Kuriyama, S;Tanaka, M;Miura, M;Nanjyo, H;Iwabuchi, Y;Shibata, H;, Cancer Sci. ,PubMed ID 30024080 [Negative Control]
Hyaluronic acid-CD44 interactions promote BMP4/7-dependent Id1/3 expression in melanoma cells ,Wu, RL;Sedlmeier, G;Kyjacova, L;Schmaus, A;Philipp, J;Thiele, W;Garvalov, BK;Sleeman, JP;, Sci Rep ,PubMed ID 30297743 [Negative Control]
The intellectual disability gene PQBP1 rescues Alzheimer’s disease pathology ,null, Molecular Psychiatry ,PubMed ID 30283027
Glucocorticoids Induce Stress Oncoproteins Associated with Therapy-Resistance in African American and European American Prostate Cancer Cells ,null, Scientific Reports ,PubMed ID 30305646
A novel variant in TAF1 affects gene expression and is associated with X-linked TAF1 intellectual disability syndrome ,Hurst, S;Liktor-Busa, E;Moutal, A;Parker, S;Rice, S;Szelinger, S;Senner, G;Hammer, M;Johnstone, L;Ramsey, K;Narayanan, V;Perez-Miller, S;Khanna, M;Dahlin, H;Lewis, K;Craig, D;Wang, E;Khanna, R;Nelson, M;, Neuronal Signal. [Negative Control]
The PTH/PTHrP-SIK3 pathway affects skeletogenesis through altered mTOR signaling ,Csukasi, F;Duran, I;Barad, M;Barta, T;Gudernova, I;Trantirek, L;Martin, JH;Kuo, CY;Woods, J;Lee, H;Cohn, DH;Krejci, P;Krakow, D;, Sci Transl Med ,PubMed ID 30232230 [Negative Control]
GPER1 promotes estrogen receptor negative breast cancer cell migration and invasion via non-genomic activation of c-Src/NF-κB/focal adhesion kinase cascade ,Li, X;Yan, Q;Xu, X;Chen, W;Li, P;Xiang, Q;Xu, X;Fu, X;, Journal of Bio-X Research [Negative Control]
Molecular characterization of autophagic and apoptotic signaling induced by sorafenib in liver cancer cells ,Rodríguez-Hernández, MA;González, R;de la Rosa, ÁJ;Gallego, P;Ordóñez, R;Navarro-Villarán, E;Contreras, L;Rodríguez-Arribas, M;González-Gallego, J;Álamo-Martínez, JM;Marín-Gómez, LM;Del Campo, JA;Quiles, JL;Fuentes, JM;de la Cruz, J;Mauriz, JL;Padillo, FJ;Muntané, J;, J. Cell. Physiol. ,PubMed ID 30132846 [Negative Control]
The atypical cyclin CNTD2 promotes colon cancer cell proliferation and migration ,Sánchez-Botet, A;Gasa, L;Quandt, E;Hernández-Ortega, S;Jiménez, J;Mezquita, P;Carrasco-García, MÀ;Kron, SJ;Vidal, A;Villanueva, A;Ribeiro, MPC;Clotet, J;, Sci Rep ,PubMed ID 30087414 [Negative Control]
mTOR mediates a mechanism of resistance to chemotherapy and defines a rational combination strategy to treat KRAS-mutant lung cancer. ,null, Oncogene ,PubMed ID 30171261
Autophagy activation contributes to glutathione transferase Mu 1-mediated chemoresistance in hepatocellular carcinoma ,Fu, XT;Song, K;Zhou, J;Shi, YH;Liu, WR;Tian, MX;Jin, L;Shi, GM;Gao, Q;Ding, ZB;Fan, J;, Oncol Lett ,PubMed ID 29928420 [ACP1]
A novel variant in TAF1 affects gene expression and is associated with X-linked TAF1 intellectual disability syndrome ,null, Neuronal Signaling ,PubMed ID 32714589
Knockdown RIP-1 inhibits production of oxLDL-induced inflammatory cytokines and promotes ABCA1 expression in macrophages ,Liu, H;Deng, X;Zhang, L;Chen, H;He, W;Gao, G;, Int J Clin Exp Med [Negative Control]
Self-Triggered Apoptosis Enzyme Prodrug Therapy (STAEPT): Enhancing Targeted Therapies via Recurrent Bystander Killing Effect by Exploiting Caspase-Cleavable Linker ,Chung, S;Choi, J;Cho, Y;Kim, H;Won, T;Dimitrion, P;Jeon, O;Kim, S;Kim, I;Kim, S;Byun, Y;, Adv. Sci. ,PubMed ID 30027061 [Negative Control]
PTPRS Regulates Colorectal Cancer RAS Pathway Activity by Inactivating Erk and Preventing Its Nuclear Translocation ,Davis, TB;Yang, M;Schell, MJ;Wang, H;Ma, L;Pledger, WJ;Yeatman, TJ;, Sci Rep ,PubMed ID 29915291 [Negative Control]
Drug delivery using polyhistidine peptide-modified liposomes that target endogenous lysosome. ,null, Biochemical and biophysical research communications ,PubMed ID 29746864
Trafficking, localization and degradation of the Na+,HCO3- co-transporter NBCn1 in kidney and breast epithelial cells ,Olesen, CW;Vogensen, J;Axholm, I;Severin, M;Schnipper, J;Pedersen, IS;von Stemann, JH;Schrøder, JM;Christensen, DP;Pedersen, SF;, Sci Rep ,PubMed ID 29743600 [Negative Control]
The AMPK agonist 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR), but not metformin, prevents inflammation-associated cachectic muscle wasting ,Hall, DT;Griss, T;Ma, JF;Sanchez, BJ;Sadek, J;Tremblay, AMK;Mubaid, S;Omer, A;Ford, RJ;Bedard, N;Pause, A;Wing, SS;Di Marco, S;Steinberg, GR;Jones, RG;Gallouzi, IE;, EMBO Mol Med ,PubMed ID 29844217 [Negative Control]
Autophagy activation contributes to glutathione transferase Mu 1‑mediated chemoresistance in hepatocellular carcinoma ,Fu, X;Song, K;Zhou, J;Shi, Y;Liu, W;Tian, M;Jin, L;Shi, G;Gao, Q;Ding, Z;Fan, J;, Oncol Lett [Scrambled Control]
The Synergy between Palmitate and TNF-α for CCL2 Production Is Dependent on the TRIF/IRF3 Pathway: Implications for Metabolic Inflammation ,Ahmad, R;Al-Roub, A;Kochumon, S;Akther, N;Thomas, R;Kumari, M;Koshy, MS;Tiss, A;Hannun, YA;Tuomilehto, J;Sindhu, S;Rosen, ED;, J. Immunol. ,PubMed ID 29632147 [Negative Control]
Flow-dependent epigenetic regulation of IGFBP5 expression by H3K27me3 contributes to endothelial anti-inflammatory effects ,null, Theranostics ,PubMed ID 29896299
Fluorescence Imaging of Huntingtin mRNA Knockdown ,Oh, E;Liu, Y;Sonar, MV;Merry, DE;Wickstrom, E;, Bioconjug. Chem. ,PubMed ID 29451775 [Negative Control]
Hyaluronan metabolism enhanced during epidermal differentiation is suppressed by vitamin C ,Hämäläinen, L;Kärkkäinen, E;Takabe, P;Rauhala, L;Bart, G;Kärnä, R;Pasonen-Seppänen, S;Oikari, S;Tammi, MI;Tammi, RH;, Br. J. Dermatol. ,PubMed ID 29405260 [Scrambled Control]
BRE/BRCC45 regulates CDC25A stability by recruiting USP7 in response to DNA damage ,null, Nature Communications ,PubMed ID 29416040
ARHGEF39 promotes tumor progression via activation of Rac1/P38 MAPK/ATF2 signaling and predicts poor prognosis in non-small cell lung cancer patients ,Zhou, H;Cai, L;Zhang, X;Li, A;Miao, Y;Li, Q;Qiu, X;Wang, E;, Lab. Invest. ,PubMed ID 29382922 [Negative Control]
Identification of BAG3 target proteins in anaplastic thyroid cancer cells by proteomic analysis ,Galdiero, F;Bello, AM;Spina, A;Capiluongo, A;Liuu, S;De Marco, M;Rosati, A;Capunzo, M;Napolitano, M;Vuttariello, E;Monaco, M;Califano, D;Turco, MC;Chiappetta, G;Vinh, J;Chiappetta, G;, Oncotarget ,PubMed ID 29487711 [Negative Control]
cAMP signaling regulates DNA hydroxymethylation by augmenting the intracellular labile ferrous iron pool ,Camarena, V;Sant, DW;Huff, TC;Mustafi, S;Muir, RK;Aron, AT;Chang, CJ;Renslo, AR;Monje, PV;Wang, G;, Elife ,PubMed ID 29239726 [negative control]
Regulation of mesenchymal signaling in palatal mucosa differentiation ,Neupane, S;Adhikari, N;Jung, JK;An, CH;Lee, S;Jun, JH;Kim, JY;Lee, Y;Sohn, WJ;Kim, JY;, Histochem. Cell Biol. ,PubMed ID 29209830 [negative control]
ZNF750 Expression Is a Potential Prognostic Biomarker in Esophageal Squamous Cell Carcinoma ,null, Oncology ,PubMed ID 29216641
Phagocytosis of environmental or metabolic crystalline particles induces cytotoxicity by triggering necroptosis across a broad range of particle size and shape ,Honarpisheh, M;Foresto-Neto, O;Desai, J;Steiger, S;Gómez, LA;Popper, B;Boor, P;Anders, HJ;Mulay, SR;, Sci Rep ,PubMed ID 29138474 [Negative Control]
Down-regulation of Stearoyl-CoA Desaturase-1 Increases Susceptibility to Palmitic Acid-Induced Lipotoxicity in Human Trophoblast Cells ,Yang, C;Lim, W;Bazer, FW;Song, G;, The Journal of Nutritional Biochemistry ,PubMed ID 29242171 [Negative Control]
Knockdown of HIP1 expression promotes ligand‑induced endocytosis of EGFR in HeLa cells ,Li, D;Chen, F;Ding, J;Lin, N;Li, Z;Wang, X;, Oncol. Rep. ,PubMed ID 29039605 [Negative Control]
Follicular Stimulating Hormone Accelerates Atherogenesis by Increasing Endothelial VCAM-1 Expression ,Li, X;Chen, W;Li, P;Wei, J;Cheng, Y;Liu, P;Yan, Q;Xu, X;Cui, Y;Gu, Z;Simoncini, T;Fu, X;, Theranostics ,PubMed ID 29187895 [Negative Control]
N6-methyladenosine (m6A) recruits and repels proteins to regulate mRNA homeostasis ,Edupuganti, RR;Geiger, S;Lindeboom, RGH;Shi, H;Hsu, PJ;Lu, Z;Wang, SY;Baltissen, MPA;Jansen, PWTC;Rossa, M;Müller, M;Stunnenberg, HG;He, C;Carell, T;Vermeulen, M;, Nat. Struct. Mol. Biol. ,PubMed ID 28869609 [Negative Control]
RNA guanine-7 methyltransferase catalyzes the methylation of cytoplasmically recapped RNAs ,null, Nucleic Acids Research ,PubMed ID 28981715
Receptor Interacting Protein-2 acts as negative regulator for nontypeable Haemophilus influenzae-induced mucin MUC5AC expression ,Bohn, AON;Komatsu, K;Matsuyama, S;Li, JD;, ntegrative Molecular Medicine [negative control]
cAMP Signaling Regulates DNA Demethylation by Augmenting the Intracellular Labile Ferrous Iron Pool ,Camarena, V;Sant, DW;Huff, T;Mustafi, S;Muir, RK;Renslo, AR;Monje, P;Wang, G;, bioRxiv [Negative Control]
De novo triiodothyronine formation from thyrocytes activated by Thyroid Stimulating Hormone ,Citterio, CE;Veluswamy, B;Morgan, SJ;Galton, VA;Banga, JP;Atkins, S;Morishita, Y;Neumann, S;Latif, R;Gershengorn, MC;Smith, TJ;Arvan, P;, J. Biol. Chem. ,PubMed ID 28743746 [Negative Control]
Occludin regulates glucose uptake and ATP production in pericytes by influencing AMP-activated protein kinase activity ,null, Journal of Cerebral Blood Flow & Metabolism ,PubMed ID 28718701
The deubiquitinating enzymes USP4 and USP17 target hyaluronan synthase 2 and differentially affect its function ,Mehić, M;de Sa, VK;Hebestreit, S;Heldin, CH;Heldin, P;, Oncogenesis ,PubMed ID 28604766 [Negative Control]
Panobinostat Enhances Growth Suppressive Effects of Progestin on Endometrial Carcinoma by Increasing Progesterone Receptor and Mitogen-Inducible Gene-6 ,Ando, H;Miyamoto, T;Kashima, H;Higuchi, S;Ida, K;Mvunta, DH;Shiozawa, T;, Horm Cancer ,PubMed ID 28516379 [Negative Control]
Follistatin Targets Distinct Pathways To Promote Brown Adipocyte Characteristics in Brown and White Adipose Tissues ,Singh, R;Braga, M;Reddy, ST;Lee, SJ;Parveen, M;Grijalva, V;Vergnes, L;Pervin, S;, Endocrinology ,PubMed ID 28324027 [Negative Control]
TITLE: Growth hormone receptor (GHR) knockdown sensitizes human melanoma cells to chemotherapy by attenuating expression of ABC drug efflux pumps ,Basu, R;Baumgaertel, N;Wu, S;Kopchick, JJ;, researchgate.net ,PubMed ID 28293855 [Negative Control]
MiR-675-5p supports hypoxia induced epithelial to mesenchymal transition in colon cancer cells ,Costa, V;Lo Dico, A;Rizzo, A;Rajata, F;Tripodi, M;Alessandro, R;Conigliaro, A;, Oncotarget ,PubMed ID 28061476 [Negative Control]
Oleate attenuates palmitate-induced endoplasmic reticulum stress and apoptosis in placental trophoblasts ,Colvin, BN;Longtine, MS;Chen, B;Costa, ML;Nelson, DM;, Reproduction ,PubMed ID 28159805 [Negative Control]
17β-estradiol-induced ACSL4 protein expression promotes an invasive phenotype in estrogen receptor positive mammary carcinoma cells ,Belkaid, A;Ouellette, RJ;Surette, ME;, Carcinogenesis ,PubMed ID 28334272 [Negative Control]
CRIPTO and its signaling partner GRP78 drive the metastatic phenotype in human osteotropic prostate cancer ,Zoni, E;Chen, L;Karkampouna, S;Granchi, Z;Verhoef, EI;La Manna, F;Kelber, J;Pelger, RC;Henry, MD;Snaar-Jagalska, E;van Leenders, GJ;Beimers, L;Kloen, P;Gray, PC;van der Pluijm, G;Kruithof-de Julio, M;, Oncogene ,PubMed ID 28394345 [Negative Control]
EGFR/ARF6 regulation of Hh signalling stimulates oncogenic Ras tumour overgrowth ,Chabu, C;Li, DM;Xu, T;, Nat Commun ,PubMed ID 28281543 [Negative Control]
MicroRNA-340 promotes the tumor growth of human gastric cancer by inhibiting cyclin G2. ,null, Oncology reports ,PubMed ID 27374211
PUMILIO/FOXP1 signaling drives expansion of hematopoietic stem/progenitor and leukemia cells ,Naudin, C;Hattabi, A;Michelet, F;Miri-Nezhad, A;Benyoucef, A;Pflumio, F;Guillonneau, F;Fichelson, S;Vigon, I;Dusanter-Fourt, I;Lauret, E;, Blood ,PubMed ID 28232582 [Negative Control]
Interleukin-27 Enhances the Potential of Reactive Oxygen Species Generation from Monocyte-derived Macrophages and Dendritic cells by Induction of p47(phox) ,Sowrirajan, B;Saito, Y;Poudyal, D;Chen, Q;Sui, H;DeRavin, SS;Imamichi, H;Sato, T;Kuhns, DB;Noguchi, N;Malech, HL;Lane, HC;Imamichi, T;, Sci Rep ,PubMed ID 28240310 [Negative Control]
Multiple UBXN family members inhibit retrovirus and lentivirus production and canonical NFκΒ signaling by stabilizing IκBα ,Hu, Y;O'Boyle, K;Auer, J;Raju, S;You, F;Wang, P;Fikrig, E;Sutton, RE;, PLoS Pathog ,PubMed ID 28152074 [Negative Control]
STIM-1 and ORAI-1 channel mediate angiotensin-II-induced expression of Egr-1 in vascular smooth muscle cells. ,null, Journal of cellular physiology ,PubMed ID 28105751
Histone H1 and Chromosomal Protein HMGN2 Regulate Prolactin-Induced STAT5 Transcription Factor Recruitment and Function in Breast Cancer Cells ,Schauwecker, SM;Kim, JJ;Licht, JD;Clevenger, CV;, J. Biol. Chem ,PubMed ID 28035005 [Negative Control]
Systems analysis identifies miR-29b regulation of invasiveness in melanoma ,Andrews, MC;Cursons, J;Hurley, DG;Anaka, M;Cebon, JS;Behren, A;Crampin, EJ;, Mol. Cancer ,PubMed ID 27852308 [negative control siRNA]
Novel tumor suppressor microRNA at frequently deleted chromosomal region 8p21 regulates epidermal growth factor receptor in prostate cancer ,Bucay, N;Sekhon, K;Majid, S;Yamamura, S;Shahryari, V;Tabatabai, ZL;Greene, K;Tanaka, Y;Dahiya, R;Deng, G;Saini, S;, Oncotarget ,PubMed ID 27611943 [Negative Control]
LY6E: a conductor of malignant tumor growth through modulation of the PTEN/PI3K/Akt/HIF-1 axis ,Yeom, CJ;Zeng, L;Goto, Y;Morinibu, A;Zhu, Y;Shinomiya, K;Kobayashi, M;Itasaka, S;Yoshimura, M;Hur, CG;Kakeya, H;Hammond, EM;Hiraoka, M;Harada, H;, Oncotarget ,PubMed ID 27589564 [ACP1]
ERK5 kinase activity is dispensable for cellular immune response and proliferation ,Lin, EC;Amantea, CM;Nomanbhoy, TK;Weissig, H;Ishiyama, J;Hu, Y;Sidique, S;Li, B;Kozarich, JW;Rosenblum, JS;, Proc. Natl. Acad. Sci. U.S.A. ,PubMed ID 27679845 [Negative Control]
Optimization of Transfection Conditions for siRNA Screening ,Montoya, JJ;Azorsa, DO;, Methods Mol. Biol. ,PubMed ID 27581281
Crizotinib inhibits NF2-associated schwannoma through inhibition of focal adhesion kinase 1 ,Troutman, S;Moleirinho, S;Kota, S;Nettles, K;Fallahi, M;Johnson, GL;Kissil, JL;, Oncotarget ,PubMed ID 27363027 [Negative Control]
Bone marrow adipocytes promote the warburg phenotype in metastatic prostate tumors via HIF-1a activation ,Diedrich, JD;Rajagurubandara, E;Herroon, MK;Mahapatra, G;Hüttemann, M;Podgorski, I;, Oncotarget ,PubMed ID 27588494
Transcription factor TBX4 regulates myofibroblast accumulation and lung fibrosis ,Xie, T;Liang, J;Liu, N;Huan, C;Zhang, Y;Liu, W;Kumar, M;Xiao, R;D'Armiento, J;Metzger, D;Chambon, P;Papaioannou, VE;Stripp, BR;Jiang, D;Noble, PW;, J. Clin. Invest. ,PubMed ID 27400124
MicroRNA-19b inhibits proliferation of gastric cancer cells by targeting B-cell CLL/lymphoma 3 ,Wang, H;Xiong, M;Hu, Y;Sun, Y;Ma, Q;, Oncol. Rep. ,PubMed ID 27572553
CXCL12/CXCR4 Axis Activation Mediates Prostate Myofibroblast Phenoconversion through Non-Canonical EGFR/MEK/ERK Signaling ,Rodríguez-Nieves, JA;Patalano, SC;Almanza, D;Gharaee-Kermani, M;Macoska, JA;, PLoS ONE ,PubMed ID 27434301
Human cytomegalovirus may promote tumour progression by upregulating arginase-2 ,null, Oncotarget ,PubMed ID 27363017
HERG ???? NF-?B ?????????????? ,??, ;???, ;???, ;??, ;???, ;???, ;, ??????? 2016
Allosteric Modulation of the Calcium-sensing Receptor Rectifies Signaling Abnormalities Associated with G-protein α-11 Mutations Causing Hypercalcemic and Hypocalcemic Disorders * ,null, The Journal of Biological Chemistry ,PubMed ID 26994139
Caveolin-1 regulates the expression of tight junction proteins during hyperoxia-induced pulmonary epithelial barrier breakdown ,null, Respiratory Research ,PubMed ID 27176222
OCT-4: a novel estrogen receptor-α collaborator that promotes tamoxifen resistance in breast cancer cells. ,null, Oncogene ,PubMed ID 27065334
Mild endothelial dysfunction in Sirt3 knockout mice fed a high-cholesterol diet: protective role of a novel C/EBP-β-dependent feedback regulation of SOD2 ,null, Basic Research in Cardiology ,PubMed ID 27071400
AIM2 Inflammasome Mediates Arsenic-induced Secretion of IL-1 beta and IL-18 ,Zhang, M;Qi, Y;Li, H;Cui, J;Dai, L;Frank, JA;, OncoImmunology
Sclerostin inhibition promotes TNF-dependent inflammatory joint destruction ,Wehmeyer, C;Frank, S;Beckmann, D;, cience Translational Medicine ,PubMed ID 27089204
MAPK1E322K mutation increases head and neck squamous cell carcinoma sensitivity to erlotinib through enhanced secretion of amphiregulin ,Wen, Y;Li, H;Zeng, Y;Wen, W;Pendleton, KP;Lui, VW;Egloff, AM;Grandis, JR;, Oncotarget ,PubMed ID 27004400
Brother of the regulator of the imprinted site (BORIS) variant subfamily 6 is involved in cervical cancer stemness and can be a target of immunotherapy ,null, Oncotarget ,PubMed ID 26849232
Oestrogens Downregulate Tissue Factor Pathway Inhibitor through Oestrogen Response Elements in the 5’-Flanking Region ,null, PLoS ONE ,PubMed ID 26999742
DNA Methylation Profiling in Human Huntington's Disease Brain ,De Souza, RA;Islam, SA;McEwen, LM;Mathelier, A;Hill, A;Mah, SM;Wasserman, WW;Kobor, MS;Leavitt, BR;, Hum. Mol. Genet. ,PubMed ID 26953320
AIM2 inflammasome mediates Arsenic-induced secretion of IL-1 β and IL-18 ,null, Oncoimmunology ,PubMed ID 27471628
Epitelial-to-mesenchimal transition and invasion are upmodulated by tumor-expressed granzyme B and inhibited by docosahexaenoic acid in human colorectal cancer cells ,null, Journal of Experimental & Clinical Cancer Research : CR ,PubMed ID 26830472
The Role of CD44 in Glucose Metabolism in Prostatic Small Cell Neuroendocrine Carcinoma ,null, Molecular cancer research : MCR ,PubMed ID 26832214
Nuclear TRAF3 is a negative regulator of CREB in B cells ,Mambetsariev, N;Lin, WW;Stunz, LL;Hanson, BM;Hildebrand, JM;Bishop, GA;, Proc. Natl. Acad. Sci. U.S.A. ,PubMed ID 26755589 [SR30004]
SMN affects membrane remodelling and anchoring of the protein synthesis machinery ,Francesca, G;Cinzia, P;Antonella, B;Stefano, FV;Teresa, CM;Tiziano, I;Annalisa, O;Martine, AT;Nicoletta, C;Nadia, C;Lucia, M;Claudio, P;Grazia, DC;, J. Cell. Sci. ,PubMed ID 26743087 [SR30004]
Dynamin-2 is a novel NOS1β interacting protein and negative regulator in the collecting duct ,null, American Journal of Physiology - Regulatory, Integrative and Comparative Physiology ,PubMed ID 26791826
Silencing of Eag1 Gene Inhibits Osteosarcoma Proliferation and Migration by Targeting STAT3-VEGF Pathway ,null, BioMed Research International ,PubMed ID 26783521
SIK inhibition in human myeloid cells modulates TLR and IL-1R signaling and induces an anti-inflammatory phenotype ,Lombardi, MS;Gilliéron, C;Dietrich, D;Gabay, C;, J. Leukoc. Biol. ,PubMed ID 26590148 [SR30004]
HIF1a deficiency reduces inflammation in a mouse model of proximal colon cancer ,Mladenova, DN;Dahlstrom, JE;Tran, PN;Benthani, F;Bean, EG;Ng, I;Pangon, L;Currey, N;Kohonen-Corish, MR;, Dis Model Mech ,PubMed ID 26183215
RUNX2 and TAZ-dependent signaling pathways regulate soluble E-Cadherin levels and tumorsphere formation in breast cancer cells ,null, Oncotarget ,PubMed ID 26320173
CD90+ liver cancer cells modulate endothelial cell phenotype through the release of exosomes containing H19 lncRNA ,null, Molecular Cancer ,PubMed ID 26272696
Phosphatidic acid (PA) increases EGF receptor (EGFR) expression by stabilizing mRNA, inhibiting RNAse-A, and by inhibiting lysosomal and proteasomal degradation of the internalized EGFR ,Hatton, N;Lintz, E;Mahankali, M;Henkels, K;Gomez-Cambronero, J;, Mol. Cell. Biol. ,PubMed ID 26124282 [SR30004]
SPSB1, a Novel Negative Regulator of the TGF-ß Signaling Pathway Targeting the Type II Receptor ,Liu, S;Nheu, T;Luwor, R;Nicholson, SE;Zhu, HJ;, J. Biol. Chem. ,PubMed ID 26032413 [SR30004]
Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells That Contribute to the Fibrous Cap ,Nurnberg, ST;Cheng, K;Raiesdana, A;Kundu, R;Miller, CL;Kim, JB;Arora, K;Carcamo-Oribe, I;Xiong, Y;Tellakula, N;Nanda, V;Murthy, N;Boisvert, WA;Hedin, U;Perisic, L;Aldi, S;Maegdefessel, L;Pjanic, M;Owens, GK;Tallquist, MD;Quertermous, T;, PLoS Genet. ,PubMed ID 26020946 [SR30004]
Toll-Like Receptor 9 Signaling Regulates Tissue Factor and Tissue Factor Pathway Inhibitor Expression in Human Endothelial Cells and Coagulation in Mice ,null, Critical Care Medicine ,PubMed ID 25855902
Coronary artery disease associated transcription factor TCF21 regulates smooth muscle precursor cells that contribute to the fibrous cap ,null, Genomics Data ,PubMed ID 26090325
Hypoxia enhances migration and invasion in glioblastoma by promoting a mesenchymal shift mediated by the HIF1α-ZEB1 axis. ,null, Cancer letters ,PubMed ID 25592037
Decreased DNA methylation in the promoter region of the WNT5A and GDNF genes may promote the osteogenicity of mesenchymal stem cells from patients with ossified spinal ligaments ,Chiba, N;Furukawa, KI;Takayama, S;Asari, T;Chin, S;Harada, Y;Kumagai, G;Wada, K;Tanaka, T;Ono, A;Motomura, S;Murakami, M;Ishibashi, Y;, J. Pharmacol. Sci. ,PubMed ID 25913759 [SR30004]
Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene ,Knowles, JW;Xie, W;Zhang, Z;Chennemsetty, I;Assimes, TL;Paananen, J;Hansson, O;Pankow, J;Goodarzi, MO;Carcamo-Orive, I;Morris, AP;Chen, YD;Mäkinen, VP;Ganna, A;Mahajan, A;Guo, X;Abbasi, F;Greenawalt, DM;Lum, P;Molony, C;Lind, L;Lindgren, C;Raffel, LJ;Tsao, PS;Schadt, EE;Rotter, JI;Sinaiko, A;Reaven, G;Yang, X;Hsiung, CA;Groop, L;Cordell, HJ;Laakso, M;Hao, K;Ingelsson, E;Frayling, TM;Weedon, MN;Walker, M;Quertermous, T;, J. Clin. Invest. ,PubMed ID 25798622 [SR30004]
Yes-mediated phosphorylation of focal adhesion kinase at tyrosine 861 increases metastatic potential of prostate cancer cells ,null, Oncotarget ,PubMed ID 25868388
A protein interaction between β-catenin and Dnmt1 regulates Wnt Signaling and DNA methylation in colorectal cancer cells ,null, Molecular cancer research : MCR ,PubMed ID 25753001
S100B is required for high glucose-induced pro-fibrotic gene expression and hypertrophy in mesangial cells ,Chuang, CT;Guh, JY;Lu, CY;Chen, HC;Chuang, LY;, Int. J. Mol. Med. ,PubMed ID 25482070 [SR30004]
Effects of obesity on severity of colitis and cytokine expression in mouse mesenteric fat. Potential role of adiponectin receptor 1 ,Sideri, A;Stavrakis, D;Bowe, C;Shih, DQ;Fleshner, P;Arsenescu, V;Arsenescu, R;Turner, JR;Pothoulakis, C;Karagiannides, I;, Am. J. Physiol. Gastrointest. Liver Physiol. ,PubMed ID 25591865 [SR30004]
Glucocorticoids suppress inflammation via the upregulation of negative regulator IRAK-M ,null, Nature Communications ,PubMed ID 25585690
Resveratrol Enhances Palmitate-Induced ER Stress and Apoptosis in Cancer Cells ,null, PLoS ONE ,PubMed ID 25436452
HMGB1 facilitates repair of mitochondrial DNA damage and extends the lifespan of mutant ataxin-1 knock-in mice ,null, EMBO Molecular Medicine ,PubMed ID 25510912
Lunasin Sensitivity in Non-Small Cell Lung Cancer Cells Is Linked to Suppression of Integrin Signaling and Changes in Histone Acetylation ,null, International Journal of Molecular Sciences ,PubMed ID 25530619
BDNF repairs podocyte damage by microRNA-mediated increase of actin polymerization ,Li, M;Armelloni, S;Zennaro, C;Wei, C;Corbelli, A;Ikehata, M;Berra, S;Giardino, L;Mattinzoli, D;Watanabe, S;Agostoni, C;Edefonti, A;Reiser, J;Messa, P;Rastaldi, MP;, J. Pathol. ,PubMed ID 25408545 [SR30004]
Cellular Differentiation Regulator BLIMP1 Induces Epstein-Barr Virus Lytic Reactivation in Epithelial and B Cells by Activating Transcription from both the R and Z Promoters ,null, Journal of Virology ,PubMed ID 25410866
Thyroid Hormone Increases Bulk Histones Expression by Enhancing Translational Efficiency ,null, Molecular Endocrinology ,PubMed ID 25422881
The Expression and Role of Krüppel-Like Factor 4 in Psoriasis ,null, Annals of Dermatology ,PubMed ID 25473217
TGF-β is an inducer of ZEB1-dependent mesenchymal transdifferentiation in glioblastoma that is associated with tumor invasion ,null, Cell Death & Disease ,PubMed ID 25275602
SDF1a-induced interaction of the adapter proteins Nck and HS1 facilitates actin polymerization and migration in T cells ,Lettau, M;Kabelitz, D;Janssen, O;, Eur. J. Immunol. ,PubMed ID 25359136 [PS100020]
IL-1ß induces p62/SQSTM1 and represses androgen receptor expression in prostate cancer cells ,Chang, M;Patel, V;Gwede, M;Morgado, M;Tomasevich, K;Fong, E;Farach-Carson, M;Delk, N;, J. Cell. Biochem. ,PubMed ID 25103771 [TT300001]
L-GILZ binds p53 and MDM2 and suppresses tumor growth through p53 activation in human cancer cells ,null, Cell Death and Differentiation ,PubMed ID 25168242
Functional analysis of mutant FAM20C in Raine syndrome with FGF23-related hypophosphatemia ,Kinoshita, Y;Hori, M;Taguchi, M;Fukumoto, S;, Bone July 2014 ,PubMed ID 25026495 [TCOL shRNA]
Endothelial Nitric-oxide Synthase (eNOS) Is Activated through G-protein-coupled Receptor Kinase-interacting Protein 1 (GIT1) Tyrosine Phosphorylation and Src Protein ,Liu, S;Premont, RT;Rockey, DC;, J. Biol. Chem. ,PubMed ID 24764294 [Tissue Lysate]
Macrophage-Derived Delta-like 1 Enhances Interleukin-6 and Matrix Metalloproteinase-3 Production by Fibroblast-Like Synoviocytes in Arthritic Mice ,Sekine, C;Nanki, T;Yagita, H;, Arthritis & rheumatology ,PubMed ID 24943093 [PS100001]
Molecular and Cellular Roles of PI31 (PSMF1) Protein in Regulation of Proteasome Function * ,null, The Journal of Biological Chemistry ,PubMed ID 24770418
Characterization of CACNA2D3 as a putative tumor suppressor gene in the development and progression of nasopharyngeal carcinoma. ,null, International journal of cancer ,PubMed ID 23649311
MiR-125a TNF receptor-associated factor 6 to inhibit osteoclastogenesis. ,null, Experimental cell research ,PubMed ID 24360988
Monocytes Activate Natural Killer Cells via Inflammasome-induced Interleukin 18 in Response to Hepatitis C Virus Replication ,null, Gastroenterology ,PubMed ID 24685721
TRIM5α and TRIM22 Are Differentially Regulated According to HIV-1 Infection Phase and Compartment ,null, Journal of Virology ,PubMed ID 24478420
MCPIP1 restricts HIV infection and is rapidly degraded in activated CD4+ T cells ,null, Proceedings of the National Academy of Sciences of the United States of America ,PubMed ID 24191027
MicroRNA-4723 Inhibits Prostate Cancer Growth through Inactivation of the Abelson Family of Nonreceptor Protein Tyrosine Kinases ,null, PLoS ONE ,PubMed ID 24223753
Cytosolic sulfotransferase 1A3 is induced by dopamine and protects neuronal cells from dopamine toxicity: role of D1 receptor-NMDA receptor coupling ,Sidharthan, NP;Minchin, RF;Butcher, NJ;, J Biol Chem. 2013 Oct 17 ,PubMed ID 24136195 [siRNA Scrambled Control]
Disorders with similar clinical phenotypes reveal underlying genetic interaction: SATB2 acts as an activator of the UPF3B gene ,null, Human genetics ,PubMed ID 23925499
Low Dose Ultraviolet B Irradiation Increases Hyaluronan Synthesis in Epidermal Keratinocytes via Sequential Induction of Hyaluronan Synthases Has1–3 Mediated by p38 and Ca2+/Calmodulin-dependent Protein Kinase II (CaMKII) Signaling ,Leena Rauhala, Lasse Hämäläinen, Pauliina Salonen, Geneviève Bart, Markku Tammi, Sanna Pasonen-Seppänen, and Raija Tammi, J. Biol. Chem., Jun 2013; 288: 17999 - 18012. ,PubMed ID 23645665 [control siRNA]
The C-terminal common to group 3 POTES (CtG3P): a newly discovered nucleolar marker associated with malignant progression and metastasis ,null, American Journal of Cancer Research ,PubMed ID 23841027
Src Inhibitors Suppress the Growth of Papillary Thyroid Carcinoma ,null, Head & neck ,PubMed ID 23729178
IL-27 inhibits HIV-1 infection in human macrophages by down-regulating host factor SPTBN1 during monocyte to macrophage differentiation ,null, The Journal of Experimental Medicine ,PubMed ID 23460728
Proteomics strategy to identify substrates of LNX, a PDZ domain-containing E3 ubiquitin ligase. ,null, Journal of proteome research ,PubMed ID 22889411
Combined Inhibition of IGF-1R/IR and Src Family Kinases Enhances Antitumor Effects in Prostate Cancer by Decreasing Activated Survival Pathways ,null, PLoS ONE ,PubMed ID 23300537
DENV Inhibits Type I IFN Production in Infected Cells by Cleaving Human STING ,null, PLoS Pathogens ,PubMed ID 23055924
Regulation and Gene Expression Profiling of NKG2D Positive Human Cytomegalovirus-Primed CD4+ T-Cells ,null, PLoS ONE ,PubMed ID 22870231
Inhibition of E2F1/CDK1 Pathway Attenuates Neuronal Apoptosis In Vitro and Confers Neuroprotection after Spinal Cord Injury In Vivo ,null, PLoS ONE ,PubMed ID 22848730
PTX3 Controls Activation of Matrix Metalloproteinase 1 and Apoptosis in Conjunctivochalasis Fibroblasts ,null, Investigative Ophthalmology & Visual Science ,PubMed ID 22511625
Expression of the p53 target CDIP correlates with sensitivity to TNF-alpha induced apoptosis in cancer cells ,null, Cancer Research ,PubMed ID 22549949
TSG-6 Controls Transcription and Activation of Matrix Metalloproteinase 1 in Conjunctivochalasis ,null, Investigative Ophthalmology & Visual Science ,PubMed ID 22297496
The CXCL12/CXCR4 Axis Promotes Ligand-Independent Activation of the Androgen Receptor ,null, Molecular and Cellular Endocrinology ,PubMed ID 22245379
Resveratrol-mediated autophagy requires WIPI-1-regulated LC3 lipidation in the absence of induced phagophore formation ,null, Autophagy ,PubMed ID 22082875
Identification of CTCF as a master regulator of the clustered protocadherin genes ,null, Nucleic Acids Research ,PubMed ID 22210889
The E3 Ubiquitin Ligase SMAD Ubiquitination Regulatory Factor 2 Negatively Regulates Kr?ppel-like Factor 5 Protein * ,null, The Journal of Biological Chemistry ,PubMed ID 21953463
Identification of the human PMR1 mRNA endonuclease as an alternatively processed product of the gene for peroxidasin-like protein ,null, RNA ,PubMed ID 22543864

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TT300001

siTran 1.0 siRNA transfection reagent (0.5ml)

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Trilencer-27 Fluorescent-labeled transfection control siRNA duplex - 1 nmol

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Trilencer-27 HPRT Positive control siRNA duplex - 1 nmol

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