Unc93b1 Mouse shRNA Plasmid (Locus ID 54445)
CAT#: TR515293
Unc93b1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
Need custom shRNA service?
Get a free quote
CNY 6,790.00
货期*
2周
规格
Cited in 1 publication. |
Product images
![](https://cdn.origene.com/img/defaults-img.jpg)
经常一起买 (1)
Specifications
Product Data | |
Product Name | Unc93b1 Mouse shRNA Plasmid (Locus ID 54445) |
Locus ID | 54445 |
UniProt ID | Q8VCW4 |
Synonyms | Unc-93B1; Unc93b |
Vector | pRS |
Format | Retroviral plasmids |
Kit Components | Unc93b1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 54445). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
RefSeq | BC018388, BC023731, NM_001161428, NM_019449, NM_019449.1, NM_019449.2, NM_001161428.1, BC025587 |
Summary | Plays an important role in innate and adaptive immunity by regulating nucleotide-sensing Toll-like receptor (TLR) signaling. Required for the transport of a subset of TLRs (including TLR3, TLR7 and TLR9) from the endoplasmic reticulum to endolysosomes where they can engage pathogen nucleotides and activate signaling cascades. May play a role in autoreactive B-cells removal.[UniProtKB/Swiss-Prot Function] |
shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
Performance Guaranteed | OriGene guarantees that the sequences in the shRNA expression cassettes are verified to correspond to the target gene with 100% identity. One of the four constructs at minimum are guaranteed to produce 70% or more gene expression knock-down provided a minimum transfection efficiency of 80% is achieved. Western Blot data is recommended over qPCR to evaluate the silencing effect of the shRNA constructs 72 hrs post transfection. To properly assess knockdown, the gene expression level from the included scramble control vector must be used in comparison with the target-specific shRNA transfected samples. For non-conforming shRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the shRNA kit. To arrange for a free replacement with newly designed constructs, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled shRNA control (Western Blot data preferred). |
Citations (1)
The use of this RNAi has been cited in the following citations: |
---|
Antioxidative properties of paraoxonase 2 in intestinal epithelial cells
,Louis-Philippe Précourt, Valérie Marcil, Thierry Ntimbane, Rame Taha, Jean-Claude Lavoie, Edgard Delvin, Ernest G. Seidman, Jean-François Beaulieu, and Emile Levy,
Am J Physiol Gastrointest Liver Physiol, Sep 2012; 303: G623 - G634.
[Unc93b1]
|
Documents
Product Manuals |
FAQs |
SDS |
其它Unc93b1产品
Customer
Reviews
Loading...