HOXA11 Human shRNA Plasmid Kit (Locus ID 3207)
CAT#: TR312366
HOXA11 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
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CNY 4,790.00
货期*
现货
规格
Cited in 2 publications. |
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经常一起买 (2)
Specifications
Product Data | |
Product Name | HOXA11 Human shRNA Plasmid Kit (Locus ID 3207) |
Locus ID | 3207 |
UniProt ID | P31270 |
Synonyms | HOX1; HOX1I; RUSAT1 |
Vector | pRS |
Format | Retroviral plasmids |
Kit Components | HOXA11 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 3207). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
RefSeq | NM_005523, NM_005523.1, NM_005523.2, NM_005523.3, NM_005523.4, NM_005523.5, BC040948, BC040948.1, BC033706, NM_005523.6 |
Summary | In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is involved in the regulation of uterine development and is required for female fertility. Mutations in this gene can cause radio-ulnar synostosis with amegakaryocytic thrombocytopenia. [provided by RefSeq, Jul 2008] |
shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
Performance Guaranteed | OriGene guarantees that the sequences in the shRNA expression cassettes are verified to correspond to the target gene with 100% identity. One of the four constructs at minimum are guaranteed to produce 70% or more gene expression knock-down provided a minimum transfection efficiency of 80% is achieved. Western Blot data is recommended over qPCR to evaluate the silencing effect of the shRNA constructs 72 hrs post transfection. To properly assess knockdown, the gene expression level from the included scramble control vector must be used in comparison with the target-specific shRNA transfected samples. For non-conforming shRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the shRNA kit. To arrange for a free replacement with newly designed constructs, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled shRNA control (Western Blot data preferred). |
Citations (2)
The use of this RNAi has been cited in the following citations: |
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Knockdown of Hoxa11 In Vivo in the Uterosacral Ligament and Uterus of Mice Results in Altered Collagen and Matrix Metalloproteinase Activity
,Yan Ma, Marsha Guess, Akshita Datar, Alex Hennessey, Ingrid Cardenas, Joshua Johnson, and Kathleen A. Connell,
Biol Reprod, Jul 2012; 86: 100.
[HOXA11]
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HoxA-11 and FOXO1A Cooperate to Regulate Decidual Prolactin Expression: Towards Inferring the Core Transcriptional Regulators of Decidual Genes
,Lynch VJ, Brayer K, Gellersen B, Wagner GP (2009),
PLoS ONE 4(9): e6845. doi:10.1371/journal.pone.0006845
[HOXA11]
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