ATP7B (NM_000053) Human Recombinant Protein
CAT#: TP762497
Purified recombinant protein of Human ATPase, Cu++ transporting, beta polypeptide (ATP7B), transcript variant 1, 200His-482Thr, with N-terminal His tag, expressed in E.coli, 50ug
View other "ATP7B" proteins (4)
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CNY 2,150.00
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding the region (200His-482Thr) of ATP7B
|
Tag | N-His |
Predicted MW | 31.9kDa |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 10% glycerol |
Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
Storage | Store at -80°C after receiving vials. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_000044 |
Locus ID | 540 |
UniProt ID | P35670, A0A024RDX3, B7ZLR4 |
Refseq Size | 6644 |
Cytogenetics | 13q14.3 |
Refseq ORF | 4395 |
Synonyms | PWD; WC1; WD; WND |
Summary | This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein is a monomer, and functions as a copper-transporting ATPase which exports copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease which is characterized by copper accumulation. [provided by RefSeq, Dec 2019] |
Protein Families | Druggable Genome, Transmembrane |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC424958 | ATP7B HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1,470.00 |
|
LY424958 | Transient overexpression lysate of ATPase, Cu++ transporting, beta polypeptide (ATP7B), transcript variant 1 |
CNY 4,840.00 |
|
PH323635 | ATP7B MS Standard C13 and N15-labeled recombinant protein (NP_000044) |
CNY 19,520.00 |
|
TP323635 | Recombinant protein of human ATPase, Cu++ transporting, beta polypeptide (ATP7B), transcript variant 1, 20 µg |
CNY 2,900.00 |