PMP70 (ABCD3) (NM_002858) Human Recombinant Protein
CAT#: TP762284
Purified recombinant protein of Human ATP-binding cassette, sub-family D (ALD), member 3 (ABCD3), transcript variant 1, Ile440-End, with N-terminal His tag, expressed in E.coli, 50ug
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CNY 1,950.00
货期*
现货
规格
Cited in 1 publication. |
经常一起买 (1)
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding the region(Ile440-End) of ABCD3
|
Tag | N-His |
Predicted MW | 25.2 kDa |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 50 mM Tris-HCl, pH 8.0, 8 M urea |
Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
Storage | Store at -80°C after receiving vials. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_002849 |
Locus ID | 5825 |
UniProt ID | P28288 |
Refseq Size | 3423 |
Cytogenetics | 1p21.3 |
Refseq ORF | 1977 |
Synonyms | ABC43; CBAS5; PMP70; PXMP1; ZWS2 |
Summary | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein likely plays an important role in peroxisome biogenesis. Mutations have been associated with some forms of Zellweger syndrome, a heterogeneous group of peroxisome assembly disorders. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008] |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | ABC transporters |
Citations (1)
The use of this Proteins has been cited in the following citations: |
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Single organelle analysis to characterize mitochondrial function and crosstalk during viral infection
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Scientific Reports
,PubMed ID 31186476
[ABCD3]
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