KLRC4 (NM_013431) Human Recombinant Protein
CAT#: TP761779
Purified recombinant protein of Human killer cell lectin-like receptor subfamily C, member 4 (KLRC4), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug
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CNY 2,040.00
货期*
2周
规格
经常一起买 (1)
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding human full-length KLRC4
|
Tag | N-GST and C-His |
Predicted MW | 46.1 kDa |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 50 mM Tris-HCl, pH 8.0, 8 M urea |
Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_038459 |
Locus ID | 8302 |
UniProt ID | O43908 |
Refseq Size | 928 |
Cytogenetics | 12p13.2 |
Refseq ORF | 474 |
Synonyms | NKG2-F; NKG2F |
Summary | Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. This gene is a member of the NKG2 group of genes that are expressed primarily in natural killer (NK) cells. These family members encode transmembrane proteins that are characterized by a type II membrane orientation (have an extracellular C-terminus) and the presence of a C-type lectin domain. This family member is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells. Read-through transcription exists between this gene and the downstream KLRK1 (killer cell lectin-like receptor subfamily K, member 1) family member. [provided by RefSeq, Dec 2010] |
Protein Families | Transmembrane |
Protein Pathways | Antigen processing and presentation |
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