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PITX2 (NM_000325) Human Recombinant Protein
CAT＃: TP761309
Purified recombinant protein of Human paired-like homeodomain 2 (PITX2), transcript variant 3, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug
View other "PITX2" proteins (9)
|
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CNY 2,040.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Species | Human |
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence |
A DNA sequence encoding human full-length PITX2
|
| Tag | N-GST and C-His |
| Predicted MW | 61.6 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Reference Data | |
| RefSeq | NP_000316 |
| Locus ID | 5308 |
| UniProt ID | Q99697, Q99697-2 |
| Refseq Size | 2337 |
| Cytogenetics | 4q25 |
| Refseq ORF | 972 |
| Synonyms | ARP1; ASGD4; Brx1; IDG2; IGDS; IGDS2; IHG2; IRID2; Otlx2; PTX2; RGS; RIEG; RIEG1; RS |
| Summary | This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. The encoded protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. This protein plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this gene are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008] |
| Protein Families | Transcription Factors |
| Protein Pathways | TGF-beta signaling pathway |
Documents
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Resources
| 蛋白相关资源 |
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC400123 | PITX2 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC407091 | PITX2 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC407092 | PITX2 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LY400123 | Transient overexpression lysate of paired-like homeodomain 2 (PITX2), transcript variant 3 |
CNY 3,080.00 |
|
| LY407091 | Transient overexpression lysate of paired-like homeodomain 2 (PITX2), transcript variant 2 |
CNY 3,080.00 |
|
| LY407092 | Transient overexpression lysate of paired-like homeodomain 2 (PITX2), transcript variant 1 |
CNY 3,080.00 |
|
| TP760239 | Recombinant protein of human paired-like homeodomain 2 (PITX2), transcript variant 2, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug |
CNY 2,040.00 |
|
| TP760287 | Recombinant protein of human paired-like homeodomain 2 (PITX2), transcript variant 1, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug |
CNY 2,040.00 |
|
| TP761571 | Purified recombinant protein of Human paired-like homeodomain 2 (PITX2), transcript variant 2, full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug |
CNY 2,040.00 |
