OGG1 (NM_016821) Human Recombinant Protein
CAT#: TP760967
Purified recombinant protein of Human 8-oxoguanine DNA glycosylase (OGG1), nuclear gene encoding mitochondrial protein, transcript variant 2a, full length, with N-terminal HIS tag, expressed in E. coli, 50ug
View other "OGG1" proteins (11)
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CNY 2,040.00
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding human full-length OGG1
|
Tag | N-His |
Predicted MW | 47.1 kDa |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 50 mM Tris-HCl, pH 8.0, 8 M urea |
Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_058214 |
Locus ID | 4968 |
UniProt ID | O15527 |
Refseq Size | 2108 |
Cytogenetics | 3p25.3 |
Refseq ORF | 1272 |
Synonyms | HMMH; HOGG1; MUTM; OGH1 |
Summary | This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined. [provided by RefSeq, Aug 2008] |
Protein Families | Druggable Genome |
Protein Pathways | Base excision repair |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC413811 | OGG1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1,470.00 |
|
LC413813 | OGG1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LC413815 | OGG1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LC413816 | OGG1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LC413835 | OGG1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LY413811 | Transient overexpression lysate of 8-oxoguanine DNA glycosylase (OGG1), nuclear gene encoding mitochondrial protein, transcript variant 2a |
CNY 4,840.00 |
|
LY413813 | Transient overexpression lysate of 8-oxoguanine DNA glycosylase (OGG1), nuclear gene encoding mitochondrial protein, transcript variant 2b |
CNY 3,080.00 |
|
LY413815 | Transient overexpression lysate of 8-oxoguanine DNA glycosylase (OGG1), nuclear gene encoding mitochondrial protein, transcript variant 2d |
CNY 3,080.00 |
|
LY413816 | Transient overexpression lysate of 8-oxoguanine DNA glycosylase (OGG1), nuclear gene encoding mitochondrial protein, transcript variant 2e |
CNY 3,080.00 |
|
LY413835 | Transient overexpression lysate of 8-oxoguanine DNA glycosylase (OGG1), nuclear gene encoding mitochondrial protein, transcript variant 1b |
CNY 3,080.00 |
|
TP720109 | Recombinant protein of human 8-oxoguanine DNA glycosylase (OGG1), nuclear gene encoding mitochondrial protein, transcript variant 1a |
CNY 1,800.00 |