DENND1B (NM_144977) Human Recombinant Protein
CAT#: TP760835
Purified recombinant protein of Human DENN/MADD domain containing 1B (DENND1B), transcript variant 2, full length, with N-terminal HIS tag, expressed in E. coli, 50ug
View other "DENND1B" proteins (2)
Need it in bulk or customized? Get a free quote |
CNY 2,040.00
货期*
2周
规格
经常一起买 (1)
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding human full-length DENND1B
|
Tag | N-His |
Predicted MW | 44.8 kDa |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol |
Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_659414 |
Locus ID | 163486 |
UniProt ID | Q6P3S1 |
Refseq Size | 2380 |
Cytogenetics | 1q31.3 |
Refseq ORF | 1188 |
Synonyms | C1ORF18; C1orf218; FAM31B |
Summary | Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]).[supplied by OMIM, Nov 2010] |
Protein Families | Transmembrane |
Documents
FAQs |
SDS |
Resources
蛋白相关资源 |
其它DENND1B产品
Customer
Reviews
Loading...