RUNX3 (NM_001031680) Human Recombinant Protein
CAT#: TP760558
Purified recombinant protein of Human runt-related transcription factor 3 (RUNX3), transcript variant 1, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
View other "RUNX3" proteins (2)
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CNY 2,040.00
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding human full-length RUNX3
|
Tag | N-His |
Predicted MW | 45.7 kDa |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 50 mM Tris-HCl, pH 8.0, 8 M urea |
Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_001026850 |
Locus ID | 864 |
UniProt ID | Q13761, A0A024RAH4 |
Refseq Size | 4340 |
Cytogenetics | 1p36.11 |
Refseq ORF | 1287 |
Synonyms | AML2; CBFA3; PEBP2aC |
Summary | This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016] |
Protein Families | Transcription Factors |
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