PFKFB2 (NM_006212) Human Recombinant Protein
CAT#: TP760443
Purified recombinant protein of Human 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (PFKFB2), transcript variant 1, with N-terminal HIS tag, expressed in E.Coli, 50ug
View other "PFKFB2" proteins (4)
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CNY 2,040.00
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding human full-length PFKFB2
|
Tag | N-His |
Predicted MW | 58.3 kDa |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol |
Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_006203 |
Locus ID | 5208 |
UniProt ID | O60825 |
Refseq Size | 7073 |
Cytogenetics | 1q32.1 |
Refseq ORF | 1515 |
Synonyms | PFK-2/FBPase-2 |
Summary | The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Protein Families | Druggable Genome |
Protein Pathways | Fructose and mannose metabolism |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC416776 | PFKFB2 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LC422707 | PFKFB2 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1,470.00 |
|
LY416776 | Transient overexpression lysate of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (PFKFB2), transcript variant 1 |
CNY 3,080.00 |
|
LY422707 | Transient overexpression lysate of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (PFKFB2), transcript variant 2 |
CNY 4,840.00 |