BNP (NPPB) (NM_002521) Human Recombinant Protein
CAT#: TP750122
Purified recombinant protein of Human natriuretic peptide B (NPPB), N-terminal His tag, expressed in E. coli, 50ug
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CNY 2,000.00
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding the region(His27-His134) of NPPB
|
Tag | N-His |
Predicted MW | 14 kDa |
Concentration | >0.05 µg/µL as determined by Bradford protein assay method. |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | PBS, pH 7.4, 10% glycerol |
Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_002512 |
Locus ID | 4879 |
UniProt ID | P16860 |
Refseq Size | 708 |
Cytogenetics | 1p36.22 |
Refseq ORF | 402 |
Synonyms | BNP; Iso-ANP |
Summary | This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The presence of myocardial injury is a significant predictor of mortality in hospitalized coronavirus disease 2019 (COVID-19) patients, and there is evidence of increased levels of natriuretic peptide B in hospitalized non-survivor COVID-19 patients. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq, Aug 2020] |
Protein Families | Druggable Genome, Secreted Protein, Stem cell - Pluripotency |
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