Cynomolgus Recombinant Protein

Specifications

Product Data
Species	Cynomolgus
Protein Source	E. coli
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Tyr29-Gln159(Gln37Glu)
Tag	C-6His
Buffer	Lyophilized from a 0.2 um filtered solution of 20mM PB , 500mM NaCl, pH 7.4.
Note	Recombinant Cynomolgus Thymic Stromal Lymphopoietin is produced by our E.coli expression system and the target gene encoding Tyr29-Gln159(Glu37Gln) is expressed with a 6His tag at the C-terminus.
Storage	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability	12 months from date of despatch
Reference Data
Synonyms	Thymic stromal lymphopoietin;Thymic stroma-derived lymphopoietin;Tslp
Summary	Thymic stromal lymphopoietin (TSLP) is a protein belonging to the cytokine family, contains 140 amino acids. It is known to play an important role in the maturation of T cell populations through activation of antigen presenting cells. TSLP induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c+ dendritic cells. It can induce allergic inflammation by directly activating mast cells. TSLP is produced mainly by non-hematopoietic cells such as fibroblasts, epithelial cells and different types of stromal or stromal-like cells. These cells are located in regions where TSLP activity is required.

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