Human Recombinant Protein

Specifications

Product Data
Species	Human
Protein Source	E. coli
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Met1-Thr322
Tag	N-GST
Buffer	Supplied as a 0.2 um filtered solution of 1M PBS, 100 mM GSH, 1% Tritonx-100, 15% Glycerol, pH 8.0.
Note	Recombinant Human Galectin-9 is produced by our E.coli expression system and the target gene encoding Met1-Thr322 is expressed with a GST tag at the N-terminus.
Storage	Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Stability	12 months from date of despatch
Reference Data
Synonyms	Galectin-9; Gal-9; Ecalectin; Tumor antigen HOM-HD-21; LGALS9; Gal-9delta5
Summary	Galectin-9 is a cytoplasmic protein that contains two galectin domains. Galectin-9 is an S-type lectin that is over-expressed in Hodgkin's disease tissue. Galectin-9 binds galactosides and has high affinity for the Forssman pentasaccharide. Galectin-9 plays a role in thymocyte-epithelial interactions relevant to the biology of the thymus and Inhibits cell proliferation. Galectin-9 is a ligand for HAVCR2/TIM3 and induces T-helper type 1 lymphocyte (Th1) death. In addition, Galectin-9 suppresses tumor cell metastasis by interfering with the associations CD44, VCAM-1, Integrin α4β1

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