Semaphorin 3A (SEMA3A) Human Recombinant Protein

Specifications

Product Data
Species	Human
Protein Source	Human
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Lys26-Phe546
Tag	C-His&Flag
Buffer	Lyophilized from a 0.2 um filtered solution of PBS, pH7.4.
Note	Recombinant Human Semaphorin 3A is produced by our Mammalian expression system and the target gene encoding Lys26-Phe546 is expressed with a 6His-Flag tag at the C-terminus.
Storage	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability	12 months from date of despatch
Reference Data
Locus ID	10371
UniProt ID	Q14563
Synonyms	Synonyms: Semaphorin III; SEMA3A; SEMAD; Hsema-I; SEMA1; SemD; Semad; coll-1 ; Hsema-III; Sema III
Summary	emaphorin-3A is a secreted protein which belongs to the semaphorin family. Semaphorins are a family of secreted and cell-bound signaling molecules defined by the presence of a common 500 aa Sema domain.This protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines.
Protein Families	Secreted Protein
Protein Pathways	Axon guidance

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