CD86 Rabbit Recombinant Protein
CAT#: TP727530
Recombinant Rabbit B7-2/CD86 (C-6His)
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CNY 3,140.00
货期*
2周
规格
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Specifications
Product Data | |
Species | Rabbit |
Protein Source | Human |
Expression cDNA Clone or AA Sequence |
Ala23-Arg246
|
Tag | C-His |
Buffer | Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4. |
Note | Recombinant Rabbit T-lymphocyte Activation Antigen CD86 is produced by our Mammalian expression system and the target gene encoding Ala23-Arg246 is expressed with a 6His tag at the C-terminus. |
Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Stability | 12 months from date of despatch |
Reference Data | |
Locus ID | 100008999 |
Synonyms | T-lymphocyte activation antigen CD86; Activation B7-2 antigen; CD86 |
Summary | T-lymphocyte activation antigen CD86 (B7-2) is a glycosylated protein in the B7 family. B7 family members are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of immune tolerance. It is highly expressed on activated antigen presenting cells. CD86 involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. It may play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. It is expressed by activated B-lymphocytes and monocytes and promoted by MARCH8 and results in endocytosis and lysosomal degradation. |
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