Scarb2 Mouse Recombinant Protein

CAT#: TP727502

Recombinant Mouse Scavenger Receptor B2/SR-B2/LIMPII/CD36L2 (C-Fc)



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CNY 3,140.00


货期*
2周

规格
    • 10 ug

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Specifications

Product Data
Species Mouse
Protein Source Human
Expression cDNA Clone or AA Sequence
Tag C-His
Buffer Lyophilized from a 0.2 um filtered solution of 50mM Tris-Citrate, 0.3M NaCl, pH6.5.
Note Recombinant Mouse Lysosomal Integral Membrane Protein II is produced by our Mammalian expression system and the target gene encoding Arg27-Thr432 is expressed with a 6His tag at the C-terminus.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability 12 months from date of despatch
Reference Data
Locus ID 12492
UniProt ID O35114
Synonyms Lysosome membrane protein 2; 85 kDa lysosomal membrane sialoglycoprotein; LGP85; Lysosome membrane protein II; LIMP II; Scavenger receptor class B member 2; Scarb2
Summary Lysosome membrane protein II (LIMPII) ,also known as SCARB2, is a type III multi-pass membrane glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes on all tissues and cell types so far examined. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is identified as a receptor for EV71 (human enterovirus species A, Enterovirus 71) and CVA16 (coxsackievirus A16) which are most frequently associated with hand, foot and mouth disease (HFMD). Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. In addition, LIMPII also has been shown to bind thrombospondin-1, may contribute to the pro-adhesive changes of activated platelets during coagulation, and inflammation.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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