Il2 Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Protein Source	E. coli
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Ala21-Gln169
Buffer	Lyophilized from a 0.2 um filtered solution of 20mM Sodium Citrate, 0.2%Tween 80,pH3.0.
Note	Recombinant Mouse Interleukin-2 is produced by our E.coli expression system and the target gene encoding Ala21-Gln169 is expressed.
Storage	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability	12 months from date of despatch
Reference Data
Locus ID	16183
UniProt ID	P04351
Synonyms	aldesleukin; interleukin 2; interleukin-2; IL-2; IL2; T-cell growth facter; T cell growth factor; TCGF
Summary	Interleukin 2 (IL 2), also termed T-cell growth factor, is a member of the cytokine family which includes IL-4, IL-7, IL-9, IL-15 and IL-21. Each member of this family has a four alpha helix bundle. IL-2 signals through the IL-2 receptor, a complex consisting of tree subunits, termed alpha, beta and gamma. The IL-2 R gamma is shared by cytokine receptors of all members of cytokine family. Mature mouse IL­2 shares 56% and 73% aa sequence identity with human and rat IL­2, respectively. IL-2 is produced by CD4+ T cell, CD8+ T cells, gamma δ T cells, B cells, dendritic cells and eosinophils, and plays a vital role in key function of the immune system, tolerance and immunity, primarily via its potent stimulatory activity for T cells.Thus, IL­2 may be a key cytokine in the natural suppression of autoimmunity.

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