DTD1 Human Recombinant Protein

Specifications

Product Data
Species	Human
Protein Source	Human
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Met1-Pro209
Tag	C-His
Buffer	Supplied as a 0.2 um filtered solution of PBS,pH7.4.
Note	Recombinant Human D-tyrosyl-tRNA(Tyr) deacylase 1 is produced by our Mammalian expression system and the target gene encoding Met1-Pro209 is expressed with a 6His tag at the C-terminus.
Storage	Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Stability	12 months from date of despatch
Reference Data
Locus ID	92675
UniProt ID	Q8TEA8
Synonyms	D-tyrosyl-tRNA(Tyr) deacylase 1;DNA-unwinding element-binding protein B;DUE-B;Histidyl-tRNA synthase-related;DTD1;C20orf88; DUEB; HARS2
Summary	D-tyrosyl-tRNA(Tyr) deacylase 1(DTD1) belongs to the DTD family, and expressed in many adult and fetal tissues such as testis, ovary, spleen in adult and fetal brain. It is a nucleus and cytoplasm located protein, and is preferentially phosphorylated in cells arrested early in S phase. DTD1 is an ATPase involved in DNA replication, it may facilitate loading of CDC45 onto pre-replication complexes. The protein may hydrolyze D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr), a possible defense mechanism against a harmful effect of D-tyrosine.

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