Cynomolgus Recombinant Protein

CAT#: TP726994

Recombinant Cynomolgus CD276(C-6His)



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CNY 3,140.00


货期*
2周

规格
    • 10 ug

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Specifications

Product Data
Species Cynomolgus
Protein Source Human
Expression cDNA Clone or AA Sequence
Tag C-His
Buffer Lyophilized from a 0.2 um filtered solution of PBS,pH7.4.
Note Recombinant Cynomolgus monkey CD276 molecule is produced by our Mammalian expression system and the target gene encoding Leu29-Glu465 is expressed with a 6His tag at the C-terminus.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability 12 months from date of despatch
Reference Data
Synonyms CD276 antigen; CD276; B7 homolog 3; B7-H3;CD276
Summary CD276, also known as B7-H3, is a member of the B7 superfamily with signature IgV and IgG regions in extracellular domains. It is a type I transmembrane protein and shares 20â€"27% amino acid identity with other B7 family members. B7-H3 is involved in the activation of T lymphocytes, and regulates murine bone formation. It is also reported that B7-H3 may play an important role in muscle-immune interactions, providing further evidence of the active role of muscle cells in local immunoregulatory processes. B7-H3 is expressed on T-cells, natural killer cells, and antigen presenting cells, as well as some non-immune cells, such as osteoblasts, fibroblasts, fibroblast-like synoviocytes and epithelial cells. High expression of B7-H3 in tumor vasculature also correlates with poor survival in patients, suggesting that it may play a role in tumor cell migration.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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