FSH beta (FSHB) Human Recombinant Protein

Specifications

Product Data
Species	Human
Protein Source	Human
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Asn19-Glu129
Tag	C-His
Buffer	Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.
Note	Recombinant Human Follicle-Stimulating Hormone Subunit beta is produced by our Mammalian expression system and the target gene encoding Asn19-Glu129 is expressed with a 6His tag at the C-terminus.
Storage	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability	12 months from date of despatch
Reference Data
Locus ID	2488
UniProt ID	P01225
Synonyms	Follitropin Subunit Beta; Follicle-Stimulating Hormone Beta Subunit; FSH-B; FSH-Beta; Follitropin Beta Chain; FSHB
Summary	Follitropin Subunit β (FSHB) is a secreted protein that belongs to the glycoprotein hormones subunit β family. The pituitary glycoprotein hormone family includes follicle-stimulating hormone, luteinizing hormone, chorionic gonadotropin, and thyroid-stimulating hormone. FSHB exists in a heterodimer of a common α chain and an unique β chain that confers biological specificity to thyrotropin, lutropin, follitropin, and gonadotropin. FSHB stimulates development of follicle and spermatogenesis in the reproductive organs. Defects in FSHB are a cause of isolated follicle-stimulating hormone deficiency (IFSHD).
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	GnRH signaling pathway, Neuroactive ligand-receptor interaction

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