Human Recombinant Protein

Specifications

Product Data
Species	Human
Protein Source	Human
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Glu27-Val331
Tag	C-Fc
Buffer	Lyophilized from a 0.2 um filtered solution of 20mM Tris-HCl,150mM NaCl,pH 8.5.
Note	Recombinant Human Sialic acid-binding Ig-like lectin 6 is produced by our Mammalian expression system and the target gene encoding Glu27-Val331 is expressed with a Fc tag at the C-terminus.
Storage	Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Stability	12 months from date of despatch
Reference Data
Synonyms	CD327; CD33 antigen-like 1; CD33L1; CDw327; OB-BP1; Siglec6; Siglec-6
Summary	Siglec-6, also known as CD327, belongs to the immunoglobulin superfamily, SIGLEC (sialic acid binding Ig-like lectin) family. Siglec-6 mediates sialic-acid dependent binding to cells. Siglec-6 binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. Siglec-6 may show increasing expression human labor and following childbirth, it has been speculated that this expression helps to slow the tempo of human labor. Siglec-6 is found on B cells and in placenta, and would seem to have a restricted specificity for the sialyl Tn antigen.

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.