Il2rb Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Protein Source	Human
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Ala27-Glu240
Tag	C-Fc
Buffer	Lyophilized from a 0.2 um filtered solution of 20mMTris-HCl,150mM NaCl,pH8.5.
Note	Recombinant Mouse Interleukin-2 Receptor subunit beta is produced by our Mammalian expression system and the target gene encoding Ala27-Glu240 is expressed with a Fc tag at the C-terminus.
Storage	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability	12 months from date of despatch
Reference Data
Locus ID	16185
UniProt ID	P16297
Synonyms	Interleukin-2 receptor subunit beta;IL2RB;IL-2 receptor subunit beta;IL-2R subunit beta;High affinity IL-2 receptor subunit beta;CD122
Summary	IL-2RB, also known asinterleukin-2 receptor subunit beta,is the receptor for interleukin-2. IL2 receptor complex is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2 receptor complex has three forms with respect to ability to bind IL2. IL-2RB is belonged to a type I membrane protein,and has a 26 residue signal peptide, a 214 residue extracellular region, a 25 residue transmembrane region and a 286 residue cytoplasmic domain. IL-2RB is the subunit critical for receptor-mediated signaling via physically or functionally coupling to other signaling molecules, such as the Jak-STAT and Src-family protein tyrosine kinase although it lacks apparent catalytic motifs.

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