CD45 (PTPRC) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Protein Source	Human 293
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Met1-Lys566
Tag	C-6His
Buffer	Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4
Note	Recombinant Human CD45 is produced by our mammalian expression system and the target gene encoding native signal Met1-Lys566 is expressed with a 6-His tag at the C-terminus.
Storage	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-5 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability	12 months from date of despatch
Reference Data
Locus ID	5788
UniProt ID	P08575
Synonyms	CD45 antigen; CD45; CD45R
Summary	CD45 is a part of the protein tyrosine phosphatase family. Depending on the relative influence, CD45 can interact with the extracellular galectin lattice or the intracellular actin cytoskeleton. That influence can cause CD45 to move in or out of the immunological synapse membrane microdomain.
Protein Families	Druggable Genome, ES Cell Differentiation/IPS, Phosphatase, Transmembrane
Protein Pathways	Cell adhesion molecules (CAMs), Fc gamma R-mediated phagocytosis, Primary immunodeficiency, T cell receptor signaling pathway

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