IFNA5 Human Recombinant Protein

Specifications

Product Data
Species	Human
Protein Source	Human 293
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Leu22-Glu189
Tag	C-6His
Buffer	Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4
Note	Recombinant Human IFNA5 is produced by our mammalian expression system and the target gene encoding native Leu22-Glu189 is expressed with a 6-His tag at the C-terminus.
Storage	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-5 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability	12 months from date of despatch
Reference Data
Locus ID	3442
UniProt ID	P01569
Synonyms	IFN-alpha Protein, IFN-alpha-5 Protein, IFN-alphaG Protein, INA5 Protein
Summary	IFNA5 is a part of the alpha/beta interferon family. This protein is the only subtype of IFNA that can be detected in a normal liver. IFNA5 are produced by macrophages and have antiviral activities. This protein is an important regulator of growth and can affect both cellular communication and signal transduction pathways. IFNA5 is also a prototypic tumor suppressor protein that will repress the clinical tumorigenic phenotype in some malignancies that are capable of differentiation.
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	Antigen processing and presentation, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity, Regulation of autophagy, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway

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