Mannan Binding Lectin (MBL2) Human Recombinant Protein

Specifications

Product Data
Species	Human
Protein Source	Human 293
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Glu21-Ile248
Tag	C-6His
Buffer	Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, 5% Trehalose, pH 7.2
Note	Recombinant Human Mannose Binding Lectin 2 is produced by our Mammalian expression system and the target gene encoding Glu21-Ile248 is expressed with a 6His tag at the C-terminus.
Storage	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-5 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability	12 months from date of despatch
Reference Data
Locus ID	4153
UniProt ID	P11226
Synonyms	Mannose-Binding Protein C; MBP-C; Collectin-1; MBP1; Mannan-Binding Protein; Mannose-Binding Lectin; MBL2; COLEC1; MBL
Summary	Human MBL-2 belongs to the collectins in the C-type lectin superfamily. This protein is a calcium-dependent lectin that is involved in natural immune defense that binds mannose, fucose, and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. This protein can bind to late apoptotic cells and possibly DNA.
Protein Families	Druggable Genome
Protein Pathways	Complement and coagulation cascades

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