Human Recombinant Protein

CAT#: TP725132

Recombinant Human Tau protein (N-His)



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CNY 3,140.00


货期*
5周

规格
    • 10 ug

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Specifications

Product Data
Species Human
Protein Source Human 293
Expression cDNA Clone or AA Sequence
Tag N-His
Buffer Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Note Recombinant Human Tau protein is produced by our Mammalian expression system and the target gene encoding Ala2-Leu441 is expressed with a 6His tag at the N-terminus.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-5 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability 12 months from date of despatch
Reference Data
Synonyms Microtubule-associated protein tau; MAPTL; Neurofibrillary tangle protein; MTBT1; Paired helical filament-tau; MAPT; Tau-F; MAPT-F
Summary Tau is a microtubule-associated protein expressed primarily in neurons. Tau promotes the assembly and stabilization of microtubules along with other MAP proteins. It is thought that other proteins can compensate for loss of Tau protein function as Tau knockout mice are viable and show no signs of neurodegeneration. There are multiple isoforms of Tau created by alternative splicing of exons 2, 3, and 10. When tau proteins are defective and no longer stabilize microtubules properly, they can result in several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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