Mouse Recombinant Protein
CAT#: TP724831
Recombinant Mouse TGF-beta RII/TGFBR2 (C-Fc)
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CNY 3,140.00
货期*
5周
规格
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Specifications
Product Data | |
Species | Mouse |
Protein Source | Human 293 |
Expression cDNA Clone or AA Sequence |
Ile24-Asp184
|
Tag | C-hFc |
Buffer | Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4 |
Note | Recombinant Mouse Transforming Growth Factor-beta Receptor Type II is produced by our Mammalian expression system and the target gene encoding Ile24-Asp184 is expressed with a Fc tag at the C-terminus. |
Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-5 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Stability | 12 months from date of despatch |
Reference Data | |
Synonyms | TGF-beta receptor type-2; TGFR-2; TGF-beta type II receptor; Transforming growth factor-betareceptor type II; TGF-beta receptor type II; TbetaR-II; Tgfbr2 |
Summary | Transforming growth factor-beta receptor type II (TGF-β RII) contains a C-terminal protein kinase domain and an N-terminal ectodomain and is the member of the transforming growth factor-beta (TGF-β) receptor subfamily. TGF-β RII is capable of binding TGF-beta 1, TGF-beta 3, and TGF-beta 5 with sufficient affinity to act as an inhibitor of these isoforms at high concentrations. TGF-β RII has a protein kinase domain that forms a heterodimeric complex with another receptor protein and bind TGF-beta. This receptor/ligand complex phosphorylates protein can enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. |
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