GPC1 Human Recombinant Protein

Specifications

Product Data
Species	Human
Protein Source	Human 293
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Asp24-Thr529
Tag	N-6His
Buffer	Lyophilized from a 0.2 um filtered solution of PBS, pH7.4.
Note	Recombinant Human Glypican-1 is produced by our Mammalian expression system and the target gene encoding Asp24-Thr529 is expressed fused with a 6His tag at the N-terminus.
Storage	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-5 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability	12 months from date of despatch
Reference Data
Locus ID	2817
UniProt ID	P35052
Synonyms	Glypican-1; GPC1
Summary	Glypican 1 is a member of the family of GPI-linked proteoglycans. GPC1 is expressed by neurons, smooth and skeletal muscle cells, keratinocytes, osteoblasts, Schwann cells, immature dendritic cells, and tumor, tumor-associated vascular endothelial cells. The function of GPC1 is complex and varied. GPC1 has been shown to interact with SLIT2. This protein plays a role in the misfolding of normal prion proteins in the cell membrane to the infectious prion form. As a proteoglycan, it appears to make use of its HS adduct to impact select growth factor activity.
Protein Families	Druggable Genome

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